Detail Information for IndEnz0008000413
IED ID IndEnz0008000413
Enzyme Type ID cellulase000413
Protein Name Effector Vd424Y
EC 3.2.1.8
Endo-1,4-beta-xylanase
Gene Name VDAG_05042
Organism Verticillium dahliae (strain VdLs.17 / ATCC MYA-4575 / FGSC 10137) (Verticillium wilt)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta sordariomyceta Sordariomycetes Hypocreomycetidae Glomerellales Plectosphaerellaceae Verticillium Verticillium dahliae (Verticillium wilt) Verticillium dahliae (strain VdLs.17 / ATCC MYA-4575 / FGSC 10137) (Verticillium wilt)
Enzyme Sequence MVSFTSLLAAFSVVSGVLTSPIAVVPEVNTALAKRTPSSTGTSGGFYYSFWTDTPNSVTYTNGDAGKFSVSWKNNNGNHVGGKGWRTGSARTIKYSGSYKPNGNSYLAIYGWTRSPLIEYYIVESFGTYNPSTGATSKGQFTVDGSVYDLYTSTRTNAPSIEGTRTFTQFWSVRRTKRTSGSVNTGAHFAAWKKAGMNLGSHDYQILAVEGYKSSGSATMTVS
Enzyme Length 223
Uniprot Accession Number G2X4G0
Absorption
Active Site ACT_SITE 119; /note=Nucleophile; /evidence=ECO:0000255|PROSITE-ProRule:PRU01097; ACT_SITE 210; /note=Proton donor; /evidence=ECO:0000255|PROSITE-ProRule:PRU01097
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.; EC=3.2.1.8; Evidence={ECO:0000255|PROSITE-ProRule:PRU01097};
DNA Binding
EC Number 3.2.1.8
Enzyme Function FUNCTION: Secreted effector that localizes to the host nucleus to contribute to the virulence process (PubMed:34233072). Induces host innate immunity responses; triggers BAK1-and SOBIR1-dependent cell death, salicylic acid signaling and jasmonic acid signaling (PubMed:34233072). {ECO:0000269|PubMed:34233072}.
Temperature Dependency
PH Dependency
Pathway PATHWAY: Glycan degradation; xylan degradation. {ECO:0000255|PROSITE-ProRule:PRU01097}.
nucleotide Binding
Features Active site (2); Chain (1); Domain (1); Mutagenesis (2); Region (1); Signal peptide (1)
Keywords Carbohydrate metabolism;Glycosidase;Host nucleus;Hydrolase;Polysaccharide degradation;Reference proteome;Secreted;Signal;Virulence;Xylan degradation
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:34233072}. Host nucleus {ECO:0000269|PubMed:34233072}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..19; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 23,968
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda