| IED ID | IndEnz0009000089 |
| Enzyme Type ID | chitinase000089 |
| Protein Name |
Probable endochitinase ARB_07371 EC 3.2.1.14 |
| Gene Name | ARB_07371 |
| Organism | Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Onygenales Arthrodermataceae (dermatophytes) Trichophyton Arthroderma benhamiae (Trichophyton mentagrophytes) Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes) |
| Enzyme Sequence | MALPKTIMAFIAFISFLVSTTFAVDVFSTTNVVTYWGQGHDQKRLSHYCQQAEHDIIVIGFVNVFPDQGKGGWPGTNFGNQCFMGTYITPEGEETELLSSCHKIIEDIPICKAAGKTIMLSLGGQAVDGSKTYSVKTRQSAVYFADFLWRAFGPVSPEWDGPRPFGDNVIDGFDFDIEANGGANYEYMVERLRSNFATDSSRQYYLSAAPQCVLPDGNLGNVISSSAFDFIFVQFYNTPSCSAFNWAQNPSKSGFTFDSWVQFIRKGASRNAKLFIGLVGDHTRVSPHGEYTKDDSNYLALPDADKLIKAYMNKYRANFGGVMIWDALTSDENKLVTGTYSSNIKRLLLNNDPSRPTTTSKTMSSTKTSMSTTTSKYTVTTSTISSTSKISSSTWSMPTMTTSTRTTSSTATRSSTIVTPSTSPNPTTSTSTTSGHQNTTATTTEIETQTSKTFITTTSIWSSGTGIGTCTGIPTITTTPRYPNATFTSDTTGSPTMSDTTITLSVTSSMHQISDTTTTIPTFSTTPIQTSDISLSMPSGTTTSKHQSSGITIPGPPHMSTTIVPASPTKPGHSTTTAIVTTTFTSVCPTGITTVTTTYTTIYCPEATPMPTAGNPPPPPGMEWTTIVTTCTKCASTSAIMTVTYPVTVPSEPMTPTQVPGTLPPPGAPGTGSGIPPPKTPSNEPGSPGTLTGIFPPKPTMSVPPEMGGNGGDRTPVYTGGAGVVSPSFSVVVIVLGSIVYHIMQ |
| Enzyme Length | 745 |
| Uniprot Accession Number | D4AT07 |
| Absorption | |
| Active Site | ACT_SITE 178; /note=Proton donor; /evidence=ECO:0000255|PROSITE-ProRule:PRU01258 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.; EC=3.2.1.14; Evidence={ECO:0000250|UniProtKB:Q873Y0}; |
| DNA Binding | |
| EC Number | 3.2.1.14 |
| Enzyme Function | FUNCTION: GPI-anchored chitinase involved in the degradation of chitin, a component of the cell walls of fungi and exoskeletal elements of some animals (including worms and arthropods). Required to reshape the cell wall at the sites where cell wall remodeling and/or cell wall maturation actively take place such as sites of conidia formation. {ECO:0000250|UniProtKB:A2R2S8, ECO:0000250|UniProtKB:Q873Y0}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Compositional bias (1); Domain (1); Glycosylation (2); Lipidation (1); Propeptide (1); Region (3); Signal peptide (1) |
| Keywords | Carbohydrate metabolism;Cell membrane;Cell wall;Chitin degradation;Chitin-binding;GPI-anchor;Glycoprotein;Glycosidase;Hydrolase;Lipoprotein;Membrane;Polysaccharide degradation;Reference proteome;Secreted;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000255}. Secreted, cell wall {ECO:0000250|UniProtKB:Q873Y0}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..23; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 79,261 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |