| IED ID | IndEnz0009000103 |
| Enzyme Type ID | chitinase000103 |
| Protein Name |
Probable di-N-acetylchitobiase 2 EC 3.2.1.- |
| Gene Name | ctbs2 DDB_G0274233 |
| Organism | Dictyostelium discoideum (Slime mold) |
| Taxonomic Lineage | cellular organisms Eukaryota Amoebozoa Evosea Eumycetozoa Dictyostelia (dictyostelid cellular slime molds) Dictyosteliales Dictyosteliaceae Dictyostelium Dictyostelium discoideum (Slime mold) |
| Enzyme Sequence | MRIILLLFLIVFVVAQSSSSSSSSGCPCDSSYLCEPLQIAPRQEFLGFSLNSTQYPNYYWNQLTTLAIFYETIEDELLCIAHENDVRLVWGTTFPIENLGNSSYIEEWIQEQIEKVQSTFTDGLNFDVESPITDPTIAQQYTELVSATNKAFKAINPFYQISIDVAWSPSCIDKRCYDYAGLASNSDFLVAMDYDERSQVFGEKVCTAGANSSPSNALAGINNFTDLGISTDQLVMGLPWYGYIYKNCLNGDEAGLETVVCQIESVPFRGANCSDAAGSEYDYSYLVQLLQDQTINSSAVQWNTEWQSPYFNYIDPITGNVDQVWFDNPQSLSIKVQLAQKLNLRGVAVWNIDFLDFSDQYNSRPMWDALASFFPQSASSEQSLN |
| Enzyme Length | 385 |
| Uniprot Accession Number | Q8T293 |
| Absorption | |
| Active Site | ACT_SITE 129; /note=Proton donor; /evidence=ECO:0000255|PROSITE-ProRule:PRU01258 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.2.1.- |
| Enzyme Function | FUNCTION: Involved in the degradation of asparagine-linked glycoproteins. May hydrolyze of N-acetyl-beta-D-glucosamine (1-4)N-acetylglucosamine chitobiose core from the reducing end of the bond. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Domain (1); Glycosylation (5); Signal peptide (1) |
| Keywords | Glycoprotein;Glycosidase;Hydrolase;Lysosome;Reference proteome;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Lysosome {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..15; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 18590548; 22120990; |
| Motif | |
| Gene Encoded By | |
| Mass | 43,203 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |