Detail Information for IndEnz0009000231
IED ID IndEnz0009000231
Enzyme Type ID chitinase000231
Protein Name Putative secretin GspD
Putative general secretion pathway protein D
Putative type II secretion system protein D
T2SS protein D
Gene Name gspD yheF b3325 JW5707
Organism Escherichia coli (strain K12)
Taxonomic Lineage cellular organisms Bacteria Proteobacteria Gammaproteobacteria Enterobacterales Enterobacteriaceae Escherichia Escherichia coli Escherichia coli (strain K12)
Enzyme Sequence MKGLNKITCCLLAALLMPCAGHAENEQYGANFNNADIRQFVEIVGQHLGKTILIDPSVQGTISVRSNDTFSQQEYYQFFLSILDLYGYSVITLDNGFLKVVRSANVKTSPGMIADSSRPGVGDELVTRIVPLENVPARDLAPLLRQMMDAGSVGNVVHYEPSNVLILTGRASTINKLIEVIKRVDVIGTEKQQIIHLEYASAEDLAEILNQLISESHGKSQMPALLSAKIVADKRTNSLIISGPEKARQRITSLLKSLDVEESEEGNTRVYYLKYAKATNLVEVLTGVSEKLKDEKGNARKPSSSGAMDNVAITADEQTNSLVITADQSVQEKLATVIARLDIRRAQVLVEAIIVEVQDGNGLNLGVQWANKNVGAQQFTNTGLPIFNAAQGVADYKKNGGITSANPAWDMFSAYNGMAAGFFNGDWGVLLTALASNNKNDILATPSIVTLDNKLASFNVGQDVPVLSGSQTTSGDNVFNTVERKTVGTKLKVTPQVNEGDAVLLEIEQEVSSVDSSSNSTLGPTFNTRTIQNAVLVKTGETVVLGGLLDDFSKEQVSKVPLLGDIPLVGQLFRYTSTERAKRNLMVFIRPTIIRDDDVYRSLSKEKYTRYRQEQQQRIDGKSKALVGSEDLPVLDENTFNSHAPAPSSR
Enzyme Length 650
Uniprot Accession Number P45758
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of folded proteins across the outer membrane. This subunit would form the outer membrane channel. {ECO:0000250|UniProtKB:E3PJ86}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Beta strand (26); Chain (1); Erroneous initiation (1); Helix (12); Region (6); Signal peptide (1); Site (1); Turn (2)
Keywords 3D-structure;Cell outer membrane;Membrane;Protein transport;Reference proteome;Signal;Transmembrane;Transmembrane beta strand;Transport
Interact With Itself
Induction INDUCTION: Silenced by the DNA-binding protein H-NS under standard growth conditions. {ECO:0000269|PubMed:11118204}.
Subcellular Location SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000305|PubMed:28067918}. Note=Most of the protein is in the periplasm which it traverses to contact proteins of the cell inner membrane. {ECO:0000305|PubMed:28067918}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..23; /evidence=ECO:0000255
Structure 3D Electron microscopy (1)
Cross Reference PDB 5WQ7;
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 70,698
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda