| IED ID | IndEnz0009000280 |
| Enzyme Type ID | chitinase000280 |
| Protein Name |
Chitinase-like protein Idgf4 Imaginal disk growth factor protein 4 |
| Gene Name | Idgf4 |
| Organism | Glossina morsitans morsitans (Savannah tsetse fly) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Mandibulata Pancrustacea Hexapoda Insecta Dicondylia Pterygota (winged insects) Neoptera Endopterygota Diptera Brachycera Muscomorpha Eremoneura Cyclorrhapha Schizophora Calyptratae Hippoboscoidea Glossinidae Glossina (tsetse flies) Glossina Glossina morsitans Glossina morsitans morsitans (Savannah tsetse fly) |
| Enzyme Sequence | MKLLLILLGALLAVLTIKRTSAVQGSNHLICYYDGTSYTREGLAKLTLNDLEPALQFCTHLVYGHAAINPSSNKLVSNNEKLDLDVGTGLYRTITGMKKKYPHLKVLLSVGGDKDEVDADNNKYLTLLESSNARIPFINSAHSMVKTYGFDGLELGWQFPKNKPKKVHGSIGKLWKGFKKIFTGDFIVDEKAEEHKEEFTALVRELKNALRPDGYILGLAVLPNVNSSLFYDVPAIVNNLDYVNLMAYDFQTPQRNPEMADFPAPIYELNERNPESNVNYQVQYWLQNHCPASKINVGIPSYGRAWKMTTDSGLTGLPPVSDADGPAAGGLQTQTEGLLSWPEVCAKLPNPANQHLKGADSPLRKVGDPTKRFGNYAYRSTDDKGENGIWVSYEDPDTAANKAAYVKTKGLGGVALVDLSFDDFRGACTGDKYPILRAIKFKFQ |
| Enzyme Length | 444 |
| Uniprot Accession Number | Q2PQM7 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Cooperates with insulin-like peptides to stimulate the proliferation, polarization and motility of imaginal disk cells. May act by stabilizing the binding of insulin-like peptides to its receptor through a simultaneous interaction with both molecules to form a multiprotein signaling complex (By similarity). {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Disulfide bond (2); Domain (1); Glycosylation (1); Signal peptide (1) |
| Keywords | Developmental protein;Disulfide bond;Glycoprotein;Secreted;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | PTM: Glycosylated. {ECO:0000250}. |
| Signal Peptide | SIGNAL 1..22; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 49,075 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |