| IED ID | IndEnz0010000051 |
| Enzyme Type ID | esterase000051 |
| Protein Name |
Pectinesterase 2 EC 3.1.1.11 Pollen allergen Ole e 11.0102 Ole e 11-2 allergen Ole e 11.0102 |
| Gene Name | |
| Organism | Olea europaea (Common olive) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae asterids lamiids Lamiales Oleaceae Oleeae Olea Olea europaea (Common olive) |
| Enzyme Sequence | MSCIAVEAVLLGILLYIPIVLSDDRAPIPANSAQLNSWFDGIIQPVAVRKATMDPALVTAEGQAKVIKLKSDGSGDFKSINEAIKSIPDDNTKRVILSFSPGNYSEKVKIGMYKHYITFYGEDPNNMPILVFGGTAAEYGTVDSATLIVESNYFSAVNLKIVNSAPRPDGKRVGAQAAALRISGDKASFYNVKIYGFQDTLCDDKGKHFYKDCYIEGTVDFIFGSGKSIFLNTELHAVPGDQPAIITAQARKTESEDTGYYFVNCRVTGGGAFLGRSWMPAAKVVFAYTEMGDAIHPEGWILVKPEHESTVRFPEYNNKGPGANMEKRAKFVKRLSDAEAKQSISLGSIEASKWLLPPRVVGLP |
| Enzyme Length | 364 |
| Uniprot Accession Number | B2VPR8 |
| Absorption | |
| Active Site | ACT_SITE 220; /evidence=ECO:0000255|PROSITE-ProRule:PRU10040 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=[(1->4)-alpha-D-galacturonosyl methyl ester](n) + n H2O = [(1->4)-alpha-D-galacturonosyl](n) + n H(+) + n methanol; Xref=Rhea:RHEA:22380, Rhea:RHEA-COMP:14570, Rhea:RHEA-COMP:14573, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:17790, ChEBI:CHEBI:140522, ChEBI:CHEBI:140523; EC=3.1.1.11; |
| DNA Binding | |
| EC Number | 3.1.1.11 |
| Enzyme Function | FUNCTION: Catalyzes the demethylesterification of homogalacturonan components of pectin. May be involved in pollen tube development (By similarity). {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | PATHWAY: Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconate from pectin: step 1/5. |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Glycosylation (1); Signal peptide (1) |
| Keywords | Allergen;Aspartyl esterase;Direct protein sequencing;Glycoprotein;Hydrolase;Secreted;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | PTM: Glycosylated. {ECO:0000269|PubMed:20491902}. |
| Signal Peptide | SIGNAL 1..22; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 39,653 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | RHEA:22380 |
| Cross Reference Brenda | 3.1.1.11; |