| IED ID | IndEnz0010000078 |
| Enzyme Type ID | esterase000078 |
| Protein Name |
Esterase SG1 EC 3.1.1.1 Carboxylic-ester hydrolase Fragment |
| Gene Name | SG1 |
| Organism | Schizaphis graminum (Green bug aphid) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Mandibulata Pancrustacea Hexapoda Insecta Dicondylia Pterygota (winged insects) Neoptera Paraneoptera Hemiptera Sternorrhyncha Aphidomorpha (aphids) Aphidoidea Aphididae (aphids) Aphidinae Aphidini Schizaphis Schizaphis graminum (Green bug aphid) |
| Enzyme Sequence | MSNTCRIVLFYLITCIFTCSASDAPKVRVNSGDIAGGYEYTYSGRKIYSFLGIPYASPPVQNYRFKEPQPVKPWLGTWNATIPGSSCMGPDYESNFKLVGQEDCLYLNVYTPKLPRENTPDDLMDVVVHIHGGAFMSGEGISLGPQYLLDINNFVYVTINYRVGVLGFATTGDNILPANNGMKDQVAALKWIQQNIVA |
| Enzyme Length | 198 |
| Uniprot Accession Number | P81429 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=a carboxylic ester + H2O = a carboxylate + an alcohol + H(+); Xref=Rhea:RHEA:21164, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:29067, ChEBI:CHEBI:30879, ChEBI:CHEBI:33308; EC=3.1.1.1; Evidence={ECO:0000255|PROSITE-ProRule:PRU10039}; |
| DNA Binding | |
| EC Number | 3.1.1.1 |
| Enzyme Function | FUNCTION: Overproduction of nonspecific esterases is a common mechanism of resistance to organophosphate insecticides. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Disulfide bond (1); Glycosylation (1); Non-terminal residue (1); Sequence conflict (2); Signal peptide (1) |
| Keywords | Direct protein sequencing;Disulfide bond;Glycoprotein;Hydrolase;Serine esterase;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..21; /evidence=ECO:0000269|PubMed:10612041 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 21,897 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | RHEA:21164 |
| Cross Reference Brenda |