| IED ID | IndEnz0010000128 |
| Enzyme Type ID | esterase000128 |
| Protein Name |
Acetylajmalan esterase EC 3.1.1.80 Fragment |
| Gene Name | AAE |
| Organism | Rauvolfia verticillata (Common devil-pepper) (Dissolena verticillata) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae asterids lamiids Gentianales Apocynaceae Rauvolfioideae Vinceae Rauvolfiinae Rauvolfia Rauvolfia verticillata (Common devil-pepper) (Dissolena verticillata) |
| Enzyme Sequence | NALFILGNIGNNDVNYAFPDRAIEEIRFYVPFITEAVANATREIIR |
| Enzyme Length | 46 |
| Uniprot Accession Number | P86830 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=17-O-acetylajmaline + H2O = acetate + ajmaline + H(+); Xref=Rhea:RHEA:22124, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30089, ChEBI:CHEBI:58567, ChEBI:CHEBI:58679; EC=3.1.1.80; Evidence={ECO:0000250|UniProtKB:Q3MKY2, ECO:0000269|PubMed:16133216}; CATALYTIC ACTIVITY: Reaction=17-O-acetylnorajmaline + H2O = acetate + H(+) + norajmaline; Xref=Rhea:RHEA:23796, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30089, ChEBI:CHEBI:77618, ChEBI:CHEBI:77725; EC=3.1.1.80; Evidence={ECO:0000250|UniProtKB:Q3MKY2, ECO:0000269|PubMed:16133216}; |
| DNA Binding | |
| EC Number | 3.1.1.80 |
| Enzyme Function | FUNCTION: Deacetylates 17-O-acetylajmaline and 17-O-acetylnorajmaline, but is inactive toward other acetylated alkaloids. {ECO:0000250|UniProtKB:Q3MKY2}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Glycosylation (1); Non-terminal residue (2) |
| Keywords | Alkaloid metabolism;Direct protein sequencing;Glycoprotein;Hydrolase |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 5,242 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | RHEA:22124; RHEA:23796 |
| Cross Reference Brenda |