| IED ID | IndEnz0010000306 |
| Enzyme Type ID | esterase000306 |
| Protein Name |
Acyl-coenzyme A thioesterase 9, mitochondrial Acyl-CoA thioesterase 9 EC 3.1.2.- Acyl-CoA thioester hydrolase 9 |
| Gene Name | ACOT9 |
| Organism | Bos taurus (Bovine) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Laurasiatheria Artiodactyla Ruminantia Pecora Bovidae Bovinae Bos (oxen cattle) Bos taurus (Bovine) |
| Enzyme Sequence | MRRAALRLCTLSKGLLAPSRGLTQESQNPENVFHIREVRDKLREIVGASTNWRDHVKAMEERKLLHSFLAKSQKGLPPRTMKDSYIEVFLPLGSQPELREKYLTVQNTVRFGRILEDLDSLGVLICYMHNKIHSAKMSPLSIVTALVDKIDMCKKNLSPEQDIKFSGHVSWVGKTSMEVKMHMFQLHGNDFSPVLDATFVMVARDSENKGPAFVNPLILESPEEEELFQQGELNKGRRVAFSSTSLLKMAPTAEERTTIHEMFLNTLDPKTISFRSRVLPANSVWMENSKLKSLDICHPQERNIFNRIFGGFLMRKAYELGWATACNFGGSRPFIVAVDDIMFQKPVEVGSLLFLSAQVCFTQGNYIQVRVHSEVASLQDKEHMTTNVFHFTFMSEKEVPLVFPRTYGESMLYLDGQRHFKSMSAPVTLKRNYVVEP |
| Enzyme Length | 437 |
| Uniprot Accession Number | Q3SWX2 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.1.2.- |
| Enzyme Function | FUNCTION: Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active on long chain acyl-CoAs. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Domain (2); Modified residue (1); Transit peptide (1) |
| Keywords | Acetylation;Hydrolase;Mitochondrion;Reference proteome;Repeat;Serine esterase;Transit peptide |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}. |
| Modified Residue | MOD_RES 101; /note=N6-acetyllysine; /evidence=ECO:0000250|UniProtKB:Q9Y305 |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 49,853 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |