| IED ID | IndEnz0010000475 |
| Enzyme Type ID | esterase000475 |
| Protein Name |
Probable secreted lipase ARB_00047 EC 3.1.1.1 |
| Gene Name | ARB_00047 |
| Organism | Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Onygenales Arthrodermataceae (dermatophytes) Trichophyton Arthroderma benhamiae (Trichophyton mentagrophytes) Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes) |
| Enzyme Sequence | MVVLPLFFAFFFMVQGNNYQPRDEIPYVRKYFYVGGQYADDGNGDHIFRDQMYVEHLVPTKGPIKQQPIVLLHGQAQTGTNWLNKPDGGRGWASYFIEHGYECYIVDQTSRGRSPWVPENGTIAAIPAETIQRLFTATARYKLWPEAELHTQWPGSGVIGDPIFDAYYASTVQFLKSQIQQETTIQAAGAALLDRIGRPVILVTHSQAGAHGWLVADTRPELVHSIIALEPAGPPFENVIYKGPYSRVWGLTNAPLTYSPAVVDPETEIVKQTIDDRPGSHCIIQADSPPPRQLPNLRRIRTLVVTAEASFHRPTDWCVVRYMEQAGISVDHVQLGDIGIRGNGHMLFLERNSDEIAAVLRRWMEEKDTKPAKKAQEAQGAQGAQEAQGKEKEL |
| Enzyme Length | 394 |
| Uniprot Accession Number | D4AV38 |
| Absorption | |
| Active Site | ACT_SITE 206; /note=Nucleophile; /evidence=ECO:0000250|UniProtKB:L0TC47 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=a carboxylic ester + H2O = a carboxylate + an alcohol + H(+); Xref=Rhea:RHEA:21164, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:29067, ChEBI:CHEBI:30879, ChEBI:CHEBI:33308; EC=3.1.1.1; Evidence={ECO:0000250|UniProtKB:L0TC47}; |
| DNA Binding | |
| EC Number | 3.1.1.1 |
| Enzyme Function | FUNCTION: Lipase that displays broad substrate specificity. {ECO:0000250|UniProtKB:L0TC47}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Glycosylation (1); Region (1); Signal peptide (1) |
| Keywords | Glycoprotein;Hydrolase;Lipid degradation;Lipid metabolism;Reference proteome;Secreted;Serine esterase;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:21919205}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..16; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 44,100 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | RHEA:21164 |
| Cross Reference Brenda |