Detail Information for IndEnz0010000595
IED ID IndEnz0010000595
Enzyme Type ID esterase000595
Protein Name Lysozyme C
EC 3.2.1.17
1,4-beta-N-acetylmuramidase C
Gene Name LYZ
Organism Halichoerus grypus (Gray seal) (Phoca grypus)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Laurasiatheria Carnivora Caniformia Phocidae (true seals) Halichoerus Halichoerus grypus (Gray seal) (Phoca grypus)
Enzyme Sequence MKALLLLGLLLLSVTVQGKIFERCDLARTLKRLGLAGFKGVSLANWMCLAKWESNYNTKATNYNPGSRSTDYGIFQINSRYWCNDGKTPRAVNACHIPCSDLLKDDITQAVACAKRVVSDPNGIRAWVAWRAHCENQDVSQYVRNCGV
Enzyme Length 148
Uniprot Accession Number Q659U5
Absorption
Active Site ACT_SITE 53; /evidence=ECO:0000255|PROSITE-ProRule:PRU00680; ACT_SITE 71; /evidence=ECO:0000255|PROSITE-ProRule:PRU00680
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.; EC=3.2.1.17;
DNA Binding
EC Number 3.2.1.17
Enzyme Function FUNCTION: Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. {ECO:0000255|PROSITE-ProRule:PRU00680}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Chain (1); Disulfide bond (4); Domain (1); Signal peptide (1)
Keywords Antimicrobial;Bacteriolytic enzyme;Disulfide bond;Glycosidase;Hydrolase;Signal
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..18; /evidence=ECO:0000250
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 16,513
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda