| IED ID | IndEnz0010000688 |
| Enzyme Type ID | esterase000688 |
| Protein Name |
Neuroligin-like protein glit-1 Gliotactin homolog Inactive esterase glit-1 |
| Gene Name | glit-1 F55D10.3 |
| Organism | Caenorhabditis elegans |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Nematoda (roundworms) Chromadorea Rhabditida Rhabditina Rhabditomorpha Rhabditoidea Rhabditidae Peloderinae Caenorhabditis Caenorhabditis elegans |
| Enzyme Sequence | MFTGTIFNSLFTLPLVISQFVPPPTRPVDLWDPFKTTTTPFPHGGVNQGLNRDEVVVRLPLGDIVGKEVHLHNLPWTIHKDPTEELPKDGTHFDPNPLKPKNNITVFTFLGVPYAEPPTSQRRFKPPQQLTVFPGKQPYLAFNYAASCAQDVEKSPSPFVDHPYPFMVDEDCLYLNIFSPDISKNAQTTYPVIVFFHGGNFQTGSANEWPAHGLASRGMVVVTVNYRLGAFGFMSMGDSETGNYGLQDQRLALEFVKNNIVTFGGDPQAVTVVGHDAGAASIGFHMQSPYSRHLFRSAATMSGAEVSYHSYIGKTALAFNNTMKLGRYAGCTQAVAQHRWDCILTRSTGDIIDATRNIPIEYNRYLFMPTVDGKYLPGNPLWTLVNAPSGETSIMSPVPMLIGMNAQDGSEVVLEDRRLGEFSQFNDVDHEYLKSYSLEYCYRHNYSMNREATADAILSKYTFWPDRAAAWAIKENFIQFATDAYYTAPMQLSSHLHSSSGSRVFQYVNNYNFSRQHPNLLFIPDWMGVCRDCDLYLMFGYPFLPDELRPIGLRGINFTDTDRNASRTFSNIIRRFSYHQNPNFQFDGSWAAYEPRRHWYINFNYTHEEDWKIPGTLARDYRYQDVAFWNEYIPALVNYMTTTFSPENVAYRREIMVFKWITGVNVIIIALLIVLAGAFGYMVWGNKEDEEAAYKAENHQLVEYRDTGHSVSDATISSRTRSPRSRITNL |
| Enzyme Length | 730 |
| Uniprot Accession Number | Q20826 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Probable neuronal cell surface protein thought to be involved in cell-cell-interactions (Probable). Confers protection against oxidative stress (PubMed:29346364). Plays a role in protecting dopaminergic neurons against oxidative stress-induced neurodegeneration (PubMed:29346364). {ECO:0000269|PubMed:29346364, ECO:0000305}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Glycosylation (7); Mutagenesis (1); Signal peptide (1); Topological domain (2); Transmembrane (1) |
| Keywords | Cell membrane;Glycoprotein;Membrane;Reference proteome;Signal;Transmembrane;Transmembrane helix |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000255}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..18; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 12529635; 14551910; 15687263; 16884526; 17417969; 17486083; 21177967; 22180091; 22560298; 23800452; 24947438; 25487147; 26419537; |
| Motif | |
| Gene Encoded By | |
| Mass | 82,993 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |