IED ID | IndEnz0010000699 |
Enzyme Type ID | esterase000699 |
Protein Name |
Lipase 5 EC 3.1.1.3 |
Gene Name | LIP5 CAALFM_C702830CA CaJ7.0322 CaO19.12646 CaO19.5179 |
Organism | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) |
Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Saccharomycotina (true yeasts) Saccharomycetes Saccharomycetales Debaryomycetaceae Candida/Lodderomyces clade Candida Candida albicans (Yeast) Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) |
Enzyme Sequence | MLYLILFLIAPIYAGLIFPTKPSSDPFYNPPKGFENAAVGDILQSRATPKSITGGFTPLKIQNSWQLLVRSEDSFGNPNVIVTTVIEPVNADPSKIASYQVFEDAAKADCAPSYALQFGSDLTTFVTQAEMYLMAPLLDQGYYVVSPDYEGPKSTFTIGKQSGQAVLNSIRAALKSGKITNIKDDAKVVMWGYSGGSLASGWAAALQPSYAPELGGNLLGAALGGFVTNITATAQATDGTVFAGIVANALGGVANEYPEFKSILQSDTDKKSVFDEFDGHCLIDGVLNYIGTSFLTGDHKIFKTGWDILKNPKIGKVVEDNGLVYQKQLVPKIPVFIYHGSIDQIVPIVDTKKTYQNWCDAGISSLEFAEDASNGHLTEAIMGAPAALTWIIDRFDGKQTVSGCQHIQRFSNLEYPNIPSSIANYFKAAMDVVLHLGLGPDVQKDQVSPEGIKKLGSIEMRWL |
Enzyme Length | 463 |
Uniprot Accession Number | Q9P8W0 |
Absorption | |
Active Site | ACT_SITE 194; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 339; /note=Charge relay system; /evidence=ECO:0000250 |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | CATALYTIC ACTIVITY: Reaction=a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+); Xref=Rhea:RHEA:12044, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:17855, ChEBI:CHEBI:18035, ChEBI:CHEBI:28868; EC=3.1.1.3; |
DNA Binding | |
EC Number | 3.1.1.3 |
Enzyme Function | |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Active site (2); Chain (1); Glycosylation (1); Sequence conflict (1); Signal peptide (1) |
Keywords | Glycoprotein;Hydrolase;Lipid degradation;Lipid metabolism;Reference proteome;Secreted;Signal |
Interact With | |
Induction | |
Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:11131027}. |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | SIGNAL 1..14; /evidence=ECO:0000255 |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | - |
Motif | |
Gene Encoded By | |
Mass | 49,963 |
Kinetics | |
Metal Binding | |
Rhea ID | RHEA:12044 |
Cross Reference Brenda |