| IED ID | IndEnz0010000701 |
| Enzyme Type ID | esterase000701 |
| Protein Name |
Sophorolipid transporter EC 7.6.2.- |
| Gene Name | mdr |
| Organism | Starmerella bombicola (Yeast) (Candida bombicola) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Saccharomycotina (true yeasts) Saccharomycetes Saccharomycetales Saccharomycetales incertae sedis Starmerella Starmerella bombicola (Yeast) (Candida bombicola) |
| Enzyme Sequence | MVDDIQVEKREKLIETKDKLLEEKLSALDPHEANVLRSQLETKRVATSFFRLFRFCTPLDVFLEILALFFAAVHGAALPMFTLVVGAIFNTFRDFTSYDLKGNEFQHKVNHLSLYFVYIGIGMLGSAFLESFLLVDRGEVLAGRYRKHYLSAVIRQNIAFYDKLGGGEVSTRIINDTNSIQEAISDKLGNVVQGIASFIAATVISFASQWKLACILLSAVGFMVITMGTGATFMAKYQLRSDAIYSQSGATVAEEALSAVRTTVAFGAQPHLAVKYEKVLDRVVKESKRSSYSLGVMLACIWASTFWVYALALWQGSREIVSGSADVGKIIVVITAMLLGSFQLGNIAPNVRFLVKGLTAASILNEAIDRVPVIDGQSIDKGIVPQTKAVGRIELKNVKFRYPSRPDVLVLSDFSLEVPAGSTVALVGASGSGKSTIVGILERFYLPLEGSVTLDGQEISDLNTRWLRQQIGYVQQEPVLFSESIYENISYGLIGTDIEFADEHVKEAKIIQACKDANAWDFIQTLSEGIQTNVGDRGFLLSGGQKQRIAIARAIVSDPKILLLDEATSALDTKSEGIVQDALDKAAEGRTTIVVAHRLSTIKDANKIVVMSKGNVIEQGTHNELIQREGPYKALVDAQRVTKAKSTNVEVLDIEALDISPLDSLNEKFNPKDVSTLSVHSAGTQTTQPPEYQENDIPGVRNPPHSTLMTNTKLVWGLNRKEWGYILIGSLASIILGYCYPAMAIITGQTTGSMVLPPSEYGKMRHVVNIMGWWYFFVGCISFMTAFITIAALSLASDKLVKNIRLALFRQLMRMDIAFFDHKNNTPGALTSILAKEAKMIEGLSGATLGQIQQSLVTLIGGIVTGIPFNWRIGLVATSVVPVMLVCGFVRVWVLTQLSDRAREVYERSGSMASEYTSAVRTVQSLTRELDVVVKYTKTVDSQIFSSRIAIARSALYYALSEGMTPWVVALVFWWGSTVMRRGEASVAGYMTVFMAIITGSQAAGQIFSYAPNMNSAKDAARNIYRILTATPSIDVWSEEGYVAPEESVRGDIEFRHVNFRYPTRPQVPVLQDLNLTVKKGQYIALVGASGCGKSTTIGLVERFYDPLAGQVLFDGKDLREYNLNALRSHIALVQQEPMLYSGTLRENILMGWSGPESEVTQEMIEDAARKANIHEFIMSLPDGYETLSGSRGSLLSGGQKQRIAIARALIRNPKVLLLDEATSALDSESEKVVQAALDAAAKGRTTIAVAHRLSTIQKADVIYVFSGGRIVEQGDHQSLLELNGWYAELVNLQGLGEI |
| Enzyme Length | 1299 |
| Uniprot Accession Number | H6TB12 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 7.6.2.- |
| Enzyme Function | FUNCTION: Transports acidic acylated and non-acylated sophorolipids (SLs) into the extracellular space, where they can be lactonized by lactone esterase. {ECO:0000269|PubMed:23516968}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | NP_BIND 428..435; /note=ATP; /evidence=ECO:0000255|PROSITE-ProRule:PRU00434; NP_BIND 1088..1095; /note=ATP; /evidence=ECO:0000255|PROSITE-ProRule:PRU00434 |
| Features | Chain (1); Domain (4); Nucleotide binding (2); Region (1); Topological domain (13); Transmembrane (12) |
| Keywords | ATP-binding;Cell membrane;Membrane;Nucleotide-binding;Repeat;Translocase;Transmembrane;Transmembrane helix;Transport |
| Interact With | |
| Induction | INDUCTION: Induced in early stationary phase (at protein level). {ECO:0000269|PubMed:23964782}. |
| Subcellular Location | SUBCELLULAR LOCATION: Cell membrane {ECO:0000305|PubMed:23516968}; Multi-pass membrane protein {ECO:0000255}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 142,459 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |