IED ID | IndEnz0010001155 |
Enzyme Type ID | esterase001155 |
Protein Name |
GDSL esterase/lipase EC 3.1.1.- CpEST Extracellular lipase |
Gene Name | |
Organism | Carica papaya (Papaya) |
Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Caricaceae Carica Carica papaya (Papaya) |
Enzyme Sequence | MEKPSGQFLGLSLLLLPLLLPISCNAQQLFIFGDSLYDNGNKPFLATDVPSTFWPYGLSIDFPNGRWSDGRIVPDFIAEFLGIPFPPPVLDRSANFSSGVTFATADATILGTPPQTLTLGDQVKAFAQIKSTWTDAQRQKGIYMFYIGANDYLNYTNANLNATAQQQEAFVSQVIAKLKDQLLAIYGLGGRKFAFQNLAPLGCLPIVKQDFKTGNFCLPLASNLAAQHNQLLSETLENLSETLDGFNYIIYDYFNSSLRRMARPNNYGYFTTNLACCGTGSHDAFGCGFKNVHSNLCSYQRGYMFFDGRHNAEKTNEAVAHLIFSADPSVVFPMNLRELFVHP |
Enzyme Length | 343 |
Uniprot Accession Number | P86276 |
Absorption | |
Active Site | ACT_SITE 35; /note=Nucleophile; /evidence=ECO:0000250; ACT_SITE 307; /evidence=ECO:0000250; ACT_SITE 310; /evidence=ECO:0000250|UniProtKB:Q9FLN0 |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | |
DNA Binding | |
EC Number | 3.1.1.- |
Enzyme Function | FUNCTION: Has lipolytic activity towards triacylglycerols, vinyl esters and phospholipid. Of the triacylglycerols, the highest activity is towards tributyrin. {ECO:0000269|PubMed:19555778}. |
Temperature Dependency | |
PH Dependency | BIOPHYSICOCHEMICAL PROPERTIES: pH dependence: Optimum pH is 8-9. {ECO:0000269|PubMed:19555778}; |
Pathway | |
nucleotide Binding | |
Features | Active site (3); Chain (1); Glycosylation (5); Sequence conflict (1); Signal peptide (1) |
Keywords | Direct protein sequencing;Glycoprotein;Hydrolase;Lipid degradation;Lipid metabolism;Secreted;Signal |
Interact With | |
Induction | |
Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:Q9FLN0}. |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | SIGNAL 1..26; /evidence=ECO:0000255 |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | - |
Motif | |
Gene Encoded By | |
Mass | 37,991 |
Kinetics | |
Metal Binding | |
Rhea ID | |
Cross Reference Brenda |