| IED ID |
IndEnz0010001269 |
| Enzyme Type ID |
esterase001269 |
| Protein Name |
cAMP-regulated D2 protein
|
| Gene Name |
D2 DDB_G0283085 |
| Organism |
Dictyostelium discoideum (Slime mold) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Amoebozoa
Evosea
Eumycetozoa
Dictyostelia (dictyostelid cellular slime molds)
Dictyosteliales
Dictyosteliaceae
Dictyostelium
Dictyostelium discoideum (Slime mold)
|
| Enzyme Sequence |
MNKLLVFILLLLLLINISFARKRSYIKNTDASIVVTQFGAIKGIVEDTHRVFYGVPFAQPPVNQLRWENPIDLKPWENVRETLTQKSQCAQKCNLGPGVCSPIGTSEDCLYLDVFTPKDATPNSKYPVIVYIPGGAFSVGSGSVPLYDATKFAQSSVIVVNINYRLGVLGFMGTDLMHGNYGFLDQIKALEWVYNNIGSFGGNKEMITIWGESAGAFSVSAHLTSTYSRQYFNAAISSSSPLTVGLKDKTTARGNANRFATNVGCNIEDLTCLRGKSMDEILDAQEKVGLTFGDKILDAFTIWSPVIDGDIIPMQPLTAVKEGKTYDVPTIIGNVKHEAIPFIYSFFQDSVGIDYYRVLVAIVFPLNAMKILPLYPAAPRGQDSRPILSELITDYLFRCPDRYHTVTNAKKLSSPTYHYHYVHVKSTGHSLDACDDKVCHGTELSLFFNSYELMGERLDNDEKELAIDINNYIVNFATTHNPNTGLDVPVQWRQVTSTQNSTLILETTIETKDTFTNDPKCNALDLTYYRNQVRP |
| Enzyme Length |
535 |
| Uniprot Accession Number |
P18142 |
| Absorption |
|
| Active Site |
ACT_SITE 213; /note=Acyl-ester intermediate; /evidence=ECO:0000255|PROSITE-ProRule:PRU10039; ACT_SITE 338; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 440; /note=Charge relay system; /evidence=ECO:0000250 |
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
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| Enzyme Function |
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| Temperature Dependency |
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| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Active site (3); Chain (1); Disulfide bond (2); Glycosylation (1); Sequence conflict (3); Signal peptide (1) |
| Keywords |
Cytoplasmic vesicle;Disulfide bond;Glycoprotein;Hydrolase;Membrane;Reference proteome;Serine esterase;Signal;cAMP |
| Interact With |
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| Induction |
INDUCTION: Expression is strongly stimulated by periodic pulses of cAMP. |
| Subcellular Location |
SUBCELLULAR LOCATION: Cytoplasmic vesicle, esterosome membrane. Note=Membrane-enclosed crystals (esterosome). |
| Modified Residue |
|
| Post Translational Modification |
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| Signal Peptide |
SIGNAL 1..20; /evidence=ECO:0000255 |
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
14504294;
16469056;
1692327;
1968413;
|
| Motif |
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| Gene Encoded By |
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| Mass |
59,600 |
| Kinetics |
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| Metal Binding |
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| Rhea ID |
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| Cross Reference Brenda |
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