| IED ID | IndEnz0010001934 |
| Enzyme Type ID | esterase001934 |
| Protein Name |
Family of serine hydrolases 1 EC 3.1.-.- |
| Gene Name | FSH1 YHR049W |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Saccharomycotina (true yeasts) Saccharomycetes Saccharomycetales Saccharomycetaceae Saccharomyces Saccharomyces cerevisiae (Baker's yeast) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
| Enzyme Sequence | MTVQIPKLLFLHGFLQNGKVFSEKSSGIRKLLKKANVQCDYIDAPVLLEKKDLPFEMDDEKWQATLDADVNRAWFYHSEISHELDISEGLKSVVDHIKANGPYDGIVGFSQGAALSSIITNKISELVPDHPQFKVSVVISGYSFTEPDPEHPGELRITEKFRDSFAVKPDMKTKMIFIYGASDQAVPSVRSKYLYDIYLKAQNGNKEKVLAYEHPGGHMVPNKKDIIRPIVEQITSSLQEASE |
| Enzyme Length | 243 |
| Uniprot Accession Number | P38777 |
| Absorption | |
| Active Site | ACT_SITE 110; /note=Charge relay system; /evidence=ECO:0000305|PubMed:15802654; ACT_SITE 183; /note=Charge relay system; /evidence=ECO:0000305|PubMed:15802654; ACT_SITE 218; /note=Charge relay system; /evidence=ECO:0000305|PubMed:15802654 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.1.-.- |
| Enzyme Function | FUNCTION: Serine hydrolase of unknown specificity. {ECO:0000269|PubMed:14645503}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Beta strand (11); Chain (1); Helix (10); Turn (3) |
| Keywords | 3D-structure;Cytoplasm;Hydrolase;Nucleus;Reference proteome;Serine esterase |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | X-ray crystallography (1) |
| Cross Reference PDB | 1YCD; |
| Mapped Pubmed ID | 16850348; 19272921; 27693354; 31363875; |
| Motif | |
| Gene Encoded By | |
| Mass | 27,339 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |