| IED ID | IndEnz0011000040 |
| Enzyme Type ID | glucanase000040 |
| Protein Name |
Glucan endo-1,3-beta-glucosidase btgC EC 3.2.1.39 Endo-1,3-beta-glucanase btgC Laminarinase btgC |
| Gene Name | btgC AN4700 |
| Organism | Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Aspergillus Aspergillus subgen. Nidulantes Emericella nidulans (Aspergillus nidulans) Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) |
| Enzyme Sequence | MGDRSEQYGDIPPISSQHRMHGYGNNGEPAAMPGDGQQNWGSGPGIAHTHSMRTASTATPGMDNLGPSAVGGGISGIALGVANTHDRQSGIDAFRDADATLGYIPAERGYHTTGADNPYVPSPPSVGPGPDESSEGLRSHETFGSSAALSAAGAPAGNWTPPSGSRHSFLDGSYQGVASGPYQRHSAYSSQDYPADINPDDILDDGDDGFAAAPSNKPNAAGGAATGGAAGGLLGEFFGAKKAADASYDPVPGAGLPSVEKYAKPRPSGASRKRGWIIGGILAFIVIGAIVGGAVGGTLGNRRSETASESSEVSADDDTETNGDLDKNSDEIKSLMAMEGLHKVFPGMDYTPWGVQHPECDKWPPSQNNVTRDMAVLSRLTNTVRLYGTDCNQTEMVLHAIDRLELTDMKLWLGVWIDTNTTTNERQLSQLYDILDKRSDHSVFKGAIIGNEALYRAGSTKEEARKNIIDYMRQVRKHFNDHNIDIKVATSDLGDNWDETLADATDVVMSNVHPFFGGVEVSKAAGWTWSFWNSHNAPLTQGTNKGNIIAEVGWPSGGGNDCGDGANCKDDTSGAVAGVKQMNQFMADWVCPALENGTDYFWFEAFDEPWKVKFNKGDEQWEDKWGLMDPGRNLKPGIEIPDCGGKTAA |
| Enzyme Length | 649 |
| Uniprot Accession Number | Q5B430 |
| Absorption | |
| Active Site | ACT_SITE 452; /note=Proton donor; /evidence=ECO:0000250|UniProtKB:O22317; ACT_SITE 551; /note=Nucleophile; /evidence=ECO:0000250|UniProtKB:O22317 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans.; EC=3.2.1.39; |
| DNA Binding | |
| EC Number | 3.2.1.39 |
| Enzyme Function | FUNCTION: Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan. {ECO:0000269|PubMed:16844780}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Compositional bias (1); Glycosylation (4); Region (3); Topological domain (2); Transmembrane (1) |
| Keywords | Carbohydrate metabolism;Cell membrane;Cell wall biogenesis/degradation;Glycoprotein;Hydrolase;Membrane;Polysaccharide degradation;Reference proteome;Signal-anchor;Transmembrane;Transmembrane helix |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 68,963 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |