IED ID |
IndEnz0011000052 |
Enzyme Type ID |
glucanase000052 |
Protein Name |
Glucanase inhibitor protein 4
|
Gene Name |
GIP4 |
Organism |
Phytophthora infestans (Potato late blight agent) (Botrytis infestans) |
Taxonomic Lineage |
cellular organisms
Eukaryota
Sar
Stramenopiles
Oomycota
Peronosporales
Peronosporaceae
Phytophthora
Phytophthora infestans (Potato late blight agent) (Botrytis infestans)
|
Enzyme Sequence |
MKSITTASFALILFGVGAASADHASRVLVLGGGAVPSGTKTYTTGIRATIDGDSFCGGSLISPTHVLTTTACIGYTKPANWVSVGTHYLNGTHDGEQIKVVSAQNHTGFNSTSGSYDVALLRLERPSKFMPVKLPAADDSDVIPGMRSSLVGWGYTSYPNGTKAYELQGVGLEVWSNTDCARIYSLDDTMVCAGGGVGKDSCNGDTGGPLIKERGPGDEDDIVVGLVSLGSRMWCGVPRSVFACVESLGMDQLGH |
Enzyme Length |
255 |
Uniprot Accession Number |
B1AC89 |
Absorption |
|
Active Site |
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Activity Regulation |
|
Binding Site |
|
Calcium Binding |
|
catalytic Activity |
|
DNA Binding |
|
EC Number |
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Enzyme Function |
FUNCTION: Secreted effector that suppresses host plant glucan elicitor-mediated defense responses (PubMed:18624645). Targets host endoglucanases and inhibits the endoglucanase-mediated release of elicitor-active glucan oligosaccharides from P.infestans cell walls (PubMed:18624645). {ECO:0000269|PubMed:18624645}. |
Temperature Dependency |
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PH Dependency |
|
Pathway |
|
nucleotide Binding |
|
Features |
Chain (1); Disulfide bond (3); Domain (1); Glycosylation (4); Signal peptide (1) |
Keywords |
Disulfide bond;Glycoprotein;Secreted;Signal;Virulence |
Interact With |
|
Induction |
INDUCTION: Expressed during infection and the expression levels increase with disease progression. {ECO:0000269|PubMed:18624645}. |
Subcellular Location |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:18624645}. |
Modified Residue |
|
Post Translational Modification |
|
Signal Peptide |
SIGNAL 1..21; /evidence=ECO:0000255 |
Structure 3D |
|
Cross Reference PDB |
- |
Mapped Pubmed ID |
- |
Motif |
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Gene Encoded By |
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Mass |
26,504 |
Kinetics |
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Metal Binding |
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Rhea ID |
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Cross Reference Brenda |
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