| IED ID | IndEnz0011000143 |
| Enzyme Type ID | glucanase000143 |
| Protein Name |
Mutanase Pc12g07500 EC 3.2.1.59 Endo-1,3-alpha-glucanase Pc12g07500 Glucan endo-1,3-alpha-glucosidas Pc12g07500 |
| Gene Name | PCH_Pc12g07500 |
| Organism | Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255) (Penicillium chrysogenum) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Penicillium Penicillium chrysogenum species complex Penicillium rubens Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255) (Penicillium chrysogenum) |
| Enzyme Sequence | MIWKSLFSALAILTHILPALTAPALDSELSSQSEDKYVFAHFMVGIVKDYQLEDWKEDMTTAQSIGIDAFALNCASIDSYTPTQLALAYEAAEQVNFKVVISFDFAYWTNGDTEKITEYMKQYAGHPAQMQYKGAAVVSTFVGDSFNWDAVKQNTPHPIYAVPNLQDPAEATTGPAKSADGAFSWLAWPTDGGNSIIPGPMTTVWDDRFVHFLAGKTYMAPVSPWFSTHFNTKNWVFVCENLPTLRWEQMLSLQPDLIEIISWNDYGESHYIGPYSAHHSDDGSSQWATNMPHDGWRNLFKPYIAAYKSGAKTPTVEADEVVYWYRPTPKGVVCTGDTLSAPMGADMLSDSIFVATMLTSPGTLTVQSGNNAPVDIEVPAGIVTSNVTMGVGAQSFKVARDGQTILSGQGGLDVKDSCVHYNFNVYVGSTKGGDGSNTTGARGSM |
| Enzyme Length | 445 |
| Uniprot Accession Number | B6GX22 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Endohydrolysis of (1->3)-alpha-D-glucosidic linkages in isolichenin, pseudonigeran and nigeran.; EC=3.2.1.59; Evidence={ECO:0000269|PubMed:24884713}; |
| DNA Binding | |
| EC Number | 3.2.1.59 |
| Enzyme Function | FUNCTION: Hydrolyzes 1,3-alpha-glucan predominantly into pentasaccharides. May enhance the efficacy of fungal antibiotics by degrading bacterial exopolysaccharides. {ECO:0000269|PubMed:24884713}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Glycosylation (2); Signal peptide (1) |
| Keywords | Glycoprotein;Glycosidase;Hydrolase;Reference proteome;Secreted;Signal |
| Interact With | |
| Induction | INDUCTION: Expression is induced in response to the presence of B.subtilis. {ECO:0000269|PubMed:24884713}. |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:24884713}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..21; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 48,546 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda | 3.2.1.59; |