| IED ID | IndEnz0011000224 |
| Enzyme Type ID | glucanase000224 |
| Protein Name |
Probable glucan endo-1,6-beta-glucosidase B EC 3.2.1.75 Beta-1,6-glucanase B Endo-1,6-beta-D-glucanase B Endo-1,6-beta-glucanase B |
| Gene Name | exgB AFUA_2G09350 |
| Organism | Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Aspergillus Aspergillus subgen. Fumigati Neosartorya fumigata (Aspergillus fumigatus) Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus) |
| Enzyme Sequence | MIRRLAAFSALSGLATAWLPEVNKKITSTNGTNLFTSSNGKIRGVNLGSQFVFEPWIAEKAWSDMGCGGQKSEFDCVSRLGQANANSAFASHWGSWITQDDIAEMVSYGLNTIRVPVGYWMREDLVYSDSEHFPQGGLQYLENLCEWASDAGLYIIIDLHGAPGAQTPQNPFTGQYAPIAGFYQDYQFEGALKFLEWMTTNIHQNDKFRNVGMLEVVNEPVQDAGKVGSMRSSYYPNAFKRIRAAEQSLNIDRNNYLHIQMMDRLWGSGDPNESLTDTYYAAYDDHRYLKWASVAVSKDSYISTSCSDQLNSNTPTIVGEWSLSVPDNVQWNSDWSPDSNKDFYKKWFAAQVTAYERQQGWIFWTWKAQLGDYRWSYQGGLLLTRPGIGDQQVLTL |
| Enzyme Length | 396 |
| Uniprot Accession Number | Q4X1N4 |
| Absorption | |
| Active Site | ACT_SITE 219; /note=Proton donor; /evidence=ECO:0000250; ACT_SITE 320; /note=Nucleophile; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Random hydrolysis of (1->6)-linkages in (1->6)-beta-D-glucans.; EC=3.2.1.75; |
| DNA Binding | |
| EC Number | 3.2.1.75 |
| Enzyme Function | FUNCTION: Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall. Acts on lutean, pustulan and 1,6-oligo-beta-D-glucosides (By similarity). {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Glycosylation (2); Signal peptide (1) |
| Keywords | Carbohydrate metabolism;Cell wall biogenesis/degradation;Glycoprotein;Glycosidase;Hydrolase;Polysaccharide degradation;Reference proteome;Secreted;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..17; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 44,795 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |