| IED ID | IndEnz0011000278 |
| Enzyme Type ID | glucanase000278 |
| Protein Name |
Probable endo-1,3 4 -beta-glucanase ARB_01444 Endo-1,3-beta-glucanase Endo-1,4-beta-glucanase EC 3.2.1.6 Laminarinase |
| Gene Name | ARB_01444 |
| Organism | Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Onygenales Arthrodermataceae (dermatophytes) Trichophyton Arthroderma benhamiae (Trichophyton mentagrophytes) Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes) |
| Enzyme Sequence | MKPYTTLPGVAVLVSLLTQSAHAAPFPSRADVVHTREQESAARPQPIVYKHERGVSNEIQYLPPDPQGHPTIIPFPTHISYVTFNSRPGAIHPPYPHLDISEASFKAEDSTCWYRGKPCEGVPHIPIVKGFDSIEKRSPAPQRHPPAPTKATAGYQFTNCTSTSNPGPTATSPTSGIPSQPSAPPATMAGQDIFQPIAKDPIPANIKSRDDHPVKANHIENPTGPISTNKFYANFFLGNQTSTTFTHPYTMIWAKGDKNASSFGMAISHVEPSQRATGEPNNKLPGNPVRYYINPVGIKSLVLSASELKESTTMSVAKPQAFSAQAILRPTGGSSESITFPLVQGMGFITAIYNNLQPAIQSAVLFRKVEPAGSPQGGIFKYKITLEDDKNWLLYVIPENGADPKLKLEGNKLISGPTGFKGVIQVAKNPSAEEGEGIYDKSAGSYATDIKISGSVGTDGTGTYKFSFEKAGKGAPLVMYALPHHVESFDDATKNTKKNMKLSTTTKGMATACVGDSWTMVEGNLPLSMDFAPWKPGSSSQVTLSEGAKNAIKAVAGNELSQDMELQTNLNSMYFSGKGLNKFAGAIYTVQELVGDKAAASGPLNSLKESFKRFVDNKQQIPLVYDNVWKGVVSSGTYEKGDTGLDFGNTLYNDHHFHYGYFILTAAILGKLDPAWLDANKAYVNMLVRDSGNSVDNDEHFPFSRAFDWYHGHSWAKGLFESSDGKDQESTSEDTMYAYAIKMWGKTSGDKSMEARGNLMLGILARTLNNYFLMKNDNVNQPKNFIGNKVTGILFENKIDHTTYFGANLEYIQGIHMLPLLPNSAYTRSAEFVKEEWEAMFASGAAAPAEKVTGGWKGVLYANLAIIDPEASWKYFAQPSLDLSSIDGGASRIWYLAYAAGEYSTYIAL |
| Enzyme Length | 909 |
| Uniprot Accession Number | D4AZ24 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Endohydrolysis of (1->3)- or (1->4)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolyzed is itself substituted at C-3.; EC=3.2.1.6; Evidence={ECO:0000250|UniProtKB:Q5AIR7}; |
| DNA Binding | |
| EC Number | 3.2.1.6 |
| Enzyme Function | FUNCTION: Probable endo-1,3(4)-beta-glucanase involved in the cell separation process. {ECO:0000250|UniProtKB:Q5AIR7}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Compositional bias (1); Glycosylation (3); Region (1); Signal peptide (1) |
| Keywords | Cell wall;Glycoprotein;Glycosidase;Hydrolase;Reference proteome;Secreted;Signal |
| Interact With | |
| Induction | INDUCTION: Expression is down-regulated in presence of human keratinocytes. {ECO:0000269|PubMed:21247460}. |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:21919205}. Secreted, cell wall {ECO:0000250|UniProtKB:Q5AIR7}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..23; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 98,853 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |