| IED ID | IndEnz0011000299 |
| Enzyme Type ID | glucanase000299 |
| Protein Name |
Endoglucanase A EC 3.2.1.4 Cellulase A Endo-1,4-beta-glucanase A EgA |
| Gene Name | celA |
| Organism | Butyrivibrio fibrisolvens |
| Taxonomic Lineage | cellular organisms Bacteria Terrabacteria group Firmicutes Clostridia Eubacteriales Lachnospiraceae Butyrivibrio Butyrivibrio fibrisolvens |
| Enzyme Sequence | MVSKKQKFLTVILVIVLAIVIVGGVFGISFVKGRVTFPWQLQNSEAKTEQVKEPAKEEPKLVIKEKKQDESAKKEQELKKAKEEAEAAVEKETEKTEEEPVDNLLNDMKLKYYGKLAVEGSHLVDADGHEVLLMGVSTHGINWYPEYASAETIKSLRDTWGINVIRLAMYTSDYNGYCVAGKENQEKLKDIIDDAVEAATDNDMYVIIDWHTLNDADPNEYKADAIQFFGEMVRKYKDNENVIYEICNEPNGDTTWNDVRRYANEVIPVIRNVDAIILVGTPKWATDLDSVLDKPLDFDNIMYTYHFYAGTHHKAERNALRDALDEGLPVFISEYGLVDADGDGNLNEKEADYWYDMIRKEYGVSSCMWNLSNKDEGSAMINADCDKLSDFTEEDLSESAMWLIDQISQLKHSDLEQGVDWITPENNNR |
| Enzyme Length | 429 |
| Uniprot Accession Number | P22541 |
| Absorption | |
| Active Site | ACT_SITE 249; /note=Proton donor; /evidence=ECO:0000250|UniProtKB:O85465; ACT_SITE 334; /note=Nucleophile; /evidence=ECO:0000250|UniProtKB:O85465 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.; EC=3.2.1.4; |
| DNA Binding | |
| EC Number | 3.2.1.4 |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Compositional bias (1); Region (1); Signal peptide (1) |
| Keywords | Carbohydrate metabolism;Cellulose degradation;Direct protein sequencing;Glycosidase;Hydrolase;Polysaccharide degradation;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..34; /evidence=ECO:0000269|PubMed:2269875 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 48,859 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |