| IED ID |
IndEnz0011000418 |
| Enzyme Type ID |
glucanase000418 |
| Protein Name |
Beta-glucan synthesis-associated protein SKN1
|
| Gene Name |
SKN1 YGR143W |
| Organism |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Fungi
Dikarya
Ascomycota
saccharomyceta
Saccharomycotina (true yeasts)
Saccharomycetes
Saccharomycetales
Saccharomycetaceae
Saccharomyces
Saccharomyces cerevisiae (Baker's yeast)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
|
| Enzyme Sequence |
MSVRNLTNNRHSNSENSVSGSENSFYSSNEQSRQSSSLEPADGQNVRVSGNPFLGSEEFDEDYNSPSGDDERRGANEYSSSSSINYNNDPNSDTSLLANEKNSPERNGQRMSDYKGYYAKTNLTSANNLNNHNNNNYKNIISSSNDNSFASHLQPPDRNLPSHPSSNNMSSFSNNSLIKSPPPFDRYPLVGTRHISAAQSQSQNLINEKKRANMTGSSSSAHDSSLSSTNLYMGEQDFSPFGGYPASFFPLTLDEKEDDDYIHNPNVEEEAKLDRRRFVDDFKHMDRRSFLGLLGILFLFMAGIFIFIVLPAITFSGVVYHHEHVHAANSAGSSSSNTTSKSLTEYQYPQLAAIRTTLVDPDTPDSAKTRVAKDGSKWQLVFSDEFNAEGRTFYDGDDQFWTAPDIHYDATKDLEWYSPDAVTTTNGTLTLRMDAFRNHDLYYRSGMVQSWNKLCFTEGALEVSANLPNYGRVTGLWPGMWTMGNLGRPGYLASTQGVWPYSYEACDAGITPNQSSPDGISYLPGQKLSVCTCDNEDHPNQGVGRGAPEIDILEGEADTILGVGVASQSLQIAPFDIWYMPDYDFIEVYNFTTTTMNTYAGGPFQQAVSAISTLNVTWYEFGEEAGYFQKYAIEYLNDDDNGYIRWFVGENPTFTLYATSLHPSGNIDWRRISKEPMSAILNLGISNNWAYIDWQYIFFPVTMSIDYVRLYQPKGSTSITCDPEDYPTYDYIQSHLNAYYNANLTDWEQAGYTFPKNILTGGCSSSKFSLS |
| Enzyme Length |
771 |
| Uniprot Accession Number |
P33336 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Required for synthesis of the major beta-glucans of the yeast cell wall. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Compositional bias (3); Domain (1); Glycosylation (6); Modified residue (10); Region (2); Topological domain (2); Transmembrane (1) |
| Keywords |
Cell wall biogenesis/degradation;Glycoprotein;Membrane;Phosphoprotein;Reference proteome;Signal-anchor;Transmembrane;Transmembrane helix |
| Interact With |
|
| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Membrane; Single-pass type II membrane protein. |
| Modified Residue |
MOD_RES 56; /note=Phosphoserine; /evidence=ECO:0007744|PubMed:19779198; MOD_RES 65; /note=Phosphoserine; /evidence=ECO:0007744|PubMed:19779198; MOD_RES 67; /note=Phosphoserine; /evidence=ECO:0007744|PubMed:19779198; MOD_RES 92; /note=Phosphoserine; /evidence=ECO:0000250|UniProtKB:P32486; MOD_RES 103; /note=Phosphoserine; /evidence=ECO:0007744|PubMed:17287358; MOD_RES 142; /note=Phosphoserine; /evidence=ECO:0000250|UniProtKB:P32486; MOD_RES 162; /note=Phosphoserine; /evidence=ECO:0000250|UniProtKB:P32486; MOD_RES 165; /note=Phosphoserine; /evidence=ECO:0000250|UniProtKB:P32486; MOD_RES 170; /note=Phosphoserine; /evidence=ECO:0000250|UniProtKB:P32486; MOD_RES 176; /note=Phosphoserine; /evidence=ECO:0007744|PubMed:18407956 |
| Post Translational Modification |
|
| Signal Peptide |
|
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
10601196;
11805826;
14690591;
15792805;
16375675;
16429126;
16527275;
16730802;
16760306;
19783660;
19891730;
20030721;
20726898;
21694716;
22174182;
22374136;
22447934;
22564307;
22629248;
22808036;
23135325;
23419716;
23874964;
23959528;
24220500;
24828506;
27859907;
7985414;
|
| Motif |
|
| Gene Encoded By |
|
| Mass |
86,241 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
|