| IED ID | IndEnz0011000426 |
| Enzyme Type ID | glucanase000426 |
| Protein Name |
Probable glucan endo-1,3-beta-glucosidase btgC EC 3.2.1.39 Endo-1,3-beta-glucanase btgC Laminarinase btgC |
| Gene Name | btgC AFUA_5G08780 |
| Organism | Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Aspergillus Aspergillus subgen. Fumigati Neosartorya fumigata (Aspergillus fumigatus) Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus) |
| Enzyme Sequence | MSGPNRTYSFGEGDDSLAHPSSRTHAMHSQYDDVSPISDGARMNPMNGQGMDHGLASVLEDGRQGWGRSPEPSPSLLTGSSATPGMDNLGPGAVGGGISGIALSVANSHDRLSGVEALMGTDGQEANIPAERGLSTTGSDNPYVPEPPEHRYSYGSNIALGAAAAPAGQLTPGQSVSHLSSTNPSQRNLYDIPYQDVGGLNAGPYQRHSAYSSNDLPVDINPDEIVDDGDDGFVPAPNSGSGARKSQAIPAAAGGAAAGGVLGNLGGLFGGKSAADTSYGPVPGAGLEAGEKGRWVKPKPGGGNKKRGWIVGAILAFIIIGAIVGGAVGGTIGHRGNEEPSSASSASSSSTQTATEDTSVNGDLDKNSAEIKALMNNKNLHKVFPGIDYTPWGVQYPLCLKYPPSQNNVTRDMAVLTQLTNNVRLYGTDCNQTEMVLHAIDKLEIKDMKIWLGVWIDSNETTSRRQIDQLYKIIDDAKDISIFNGAIVGNEALYRAGSDKTSAQTTLINYMQEVKDHFKKKNIDLPVATSDLGDNWDATLVQAADVVMANVHPFFGGIPVDQAAAWTWRFWQDHNVALTKGTNKKQIISEVGWPSGGGNDCGQGANCPNDTAGAVAGVDELNKFMEDWVCQALDNGTDYFWFEAFDEPWKIVYNTGKENWEDKWGLMDSARNLKPGLKIPDCGGKTAT |
| Enzyme Length | 688 |
| Uniprot Accession Number | Q4WUK5 |
| Absorption | |
| Active Site | ACT_SITE 491; /note=Proton donor; /evidence=ECO:0000250|UniProtKB:O22317; ACT_SITE 590; /note=Nucleophile; /evidence=ECO:0000250|UniProtKB:O22317 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans.; EC=3.2.1.39; |
| DNA Binding | |
| EC Number | 3.2.1.39 |
| Enzyme Function | FUNCTION: Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan (By similarity). {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Compositional bias (3); Glycosylation (5); Region (4); Topological domain (2); Transmembrane (1) |
| Keywords | Carbohydrate metabolism;Cell membrane;Cell wall biogenesis/degradation;Glycoprotein;Hydrolase;Membrane;Polysaccharide degradation;Reference proteome;Signal-anchor;Transmembrane;Transmembrane helix |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 72,696 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |