| IED ID |
IndEnz0013000002 |
| Enzyme Type ID |
keratinase000002 |
| Protein Name |
Serine alkaline keratinase preproprotein
|
| Gene Name |
kerB |
| Organism |
Actinomadura keratinilytica |
| Taxonomic Lineage |
cellular organisms
Bacteria
Terrabacteria group
Actinobacteria
Actinomycetia (high G+C Gram-positive bacteria)
Streptosporangiales
Thermomonosporaceae
Actinomadura
Actinomadura keratinilytica
|
| Enzyme Sequence |
MRPSPVVSAIGTEALAFGLALAAAPGALAASGPLPQSPSPDSDVATTMAEALERDLNLTSAEAQELLTGQEAAFEADEAAAQAAGDAYAGSVFDTETLELTVMVTDAAAVQAVEATGAKADVVSHGLDGLEAVIDDLNEAAHQPGVVGWYPDITSDTVVLEVLDGAEADAEALIADAGVDASTVTIETTTQSPELYADIDAGLAYTMGGRCSVGFAATNASGQPGFYTAAHCGSVGTQVSIGNGRGVFERSVFPGNDYAWVRGTSNWTLTNLVSRYNSGFYATQSGSSTAPIGSQVCRSGSTTGWHCGTIQARNQTVSYPQGTLHSLIRTSVCARPGDSAGSFISGTQSQGVTSGGSGNCRTGGTTFYQIGNPMLNSENIRLRT |
| Enzyme Length |
384 |
| Uniprot Accession Number |
A0A2S0DFI7 |
| Absorption |
|
| Active Site |
ACT_SITE 231; /note=Charge relay system; /evidence=ECO:0000256|PIRSR:PIRSR001134-1; ACT_SITE 257; /note=Charge relay system; /evidence=ECO:0000256|PIRSR:PIRSR001134-1; ACT_SITE 339; /note=Charge relay system; /evidence=ECO:0000256|PIRSR:PIRSR001134-1 |
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
|
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Active site (3); Chain (1); Disulfide bond (3); Domain (1); Signal peptide (1) |
| Keywords |
Disulfide bond;Hydrolase;Protease;Signal |
| Interact With |
|
| Induction |
|
| Subcellular Location |
|
| Modified Residue |
|
| Post Translational Modification |
|
| Signal Peptide |
SIGNAL 1..29; /evidence=ECO:0000256|SAM:SignalP |
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
|
| Gene Encoded By |
|
| Mass |
39,112 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
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