IED ID | IndEnz0013000008 |
Enzyme Type ID | keratinase000008 |
Protein Name |
Neutral metalloproteinase EC 3.4.24.- Fragment |
Gene Name | |
Organism | Pseudomonas aeruginosa |
Taxonomic Lineage | cellular organisms Bacteria Proteobacteria Gammaproteobacteria Pseudomonadales Pseudomonadaceae Pseudomonas Pseudomonas aeruginosa group Pseudomonas aeruginosa |
Enzyme Sequence | ADLIDVSKLPSKAAQGAPGPVTLQAAVGAGGADELKAIRSTTLPNGKQVTRYEQFHNGVRVVGEAITEVKGPGKSVAAQRSGHFVANIAADLPGSTTAAVSAEQVLAQAKSLKAQGRKTENDKVELVIRLGENNIAQLVYNVSYLIPGEGLSRPHFVIDAKTGEVLDQWEGLAHAEAGGPGGNQKIGKYTYGSDYGPLIVNDRCEMDDGNVITVDMNSSTDDSKTTPFRFACPTNTYKQVNGAYSPLNDAHFFGGVVFKLYRDWFGTSPLTHKLYMKVHYGRSVENAYWDGTAMLFGDGATMFYPLVSLDVAAHEVSHGFTEQNSGLIYRGQSGGMNEAFSDMAGEAAEFYMRGKNDFLIGYDIKKGSGALRYMDQPSRDGRSIDNASQYYNGIDVHHSSGVYNRAFYLLANSPGWDTRKAFEVFVDANRYYWTATSNYNSGACGVIRSAQNRNYSAADVTRAFSTVGVTCPSAL |
Enzyme Length | 475 |
Uniprot Accession Number | E3ULB4 |
Absorption | |
Active Site | ACT_SITE 315; /evidence=ECO:0000256|PIRSR:PIRSR623612-1; ACT_SITE 397; /note=Proton donor; /evidence=ECO:0000256|PIRSR:PIRSR623612-1 |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | |
DNA Binding | |
EC Number | 3.4.24.- |
Enzyme Function | FUNCTION: Extracellular zinc metalloprotease. {ECO:0000256|RuleBase:RU366073}. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Active site (2); Disulfide bond (2); Domain (4); Non-terminal residue (1) |
Keywords | 3D-structure;Hydrolase;Metalloprotease;Protease;Secreted;Signal;Zinc |
Interact With | |
Induction | |
Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU366073}. |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | |
Structure 3D | X-ray crystallography (1) |
Cross Reference PDB | 7AJR; |
Mapped Pubmed ID | - |
Motif | |
Gene Encoded By | |
Mass | 51,295 |
Kinetics | |
Metal Binding | |
Rhea ID | |
Cross Reference Brenda |