| IED ID | IndEnz0015000040 |
| Enzyme Type ID | laccase000040 |
| Protein Name |
Laccase-4 EC 1.10.3.2 Benzenediol:oxygen oxidoreductase 4 Diphenol oxidase 4 Urishiol oxidase 4 |
| Gene Name | LAC4 Os01g0842400 LOC_Os01g62480 OsJ_003940 P0406G08.11 |
| Organism | Oryza sativa subsp. japonica (Rice) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae Liliopsida Petrosaviidae commelinids Poales Poaceae BOP clade Oryzoideae Oryzeae Oryzinae Oryza Oryza sativa (Rice) Oryza sativa subsp. japonica (Rice) |
| Enzyme Sequence | MTMAISSALPSPLLLAASLLLLIVQAQGITRHYEFNVQMANATRLCNTKSMVTVNGQCPGPELVAREGDRVVIRVTNNVAHNISLHWHGVRQVRTGWADGPAYITQCPIQTGQSYVYNFTVAGQRGTLWWHAHISWLRATVYGALVILPKLGVPYPFPAPHKEVPVIFGEWWNADTEEVVNQAVQTGGGPNVSDAFTINGLPGPLYNCSAQDTFKLKVKPGKTYMLRLINAALNEELFFAVANHTLTVVEVDAVYVKPFTVDTLVISPGQTTNVLLTAKPYYPGANFYMSAAPYSTARPGTFGNTTVAGILEYENPAMSPSAASFVKGLPLFKPTLPQLNDTDFVTNFTDKLRSLATPEYPAAVPQSVDKRFFFTVGLGTLPCPANMTCQGPNNTQMAASMNNVSFVLPARALLQSHFTGLSSGVYAPDFPVAPLSPFNYTGTPPNNTNVKTGTKLLVLRYNTSVELVMQDTSILGIESHPLHLHGFNFFVIGQGFGNYDAVNDPAKFNLVDPVERNTVGVPAGGWVAIRFLADNPGVWFMHCHLEAHTTWGLRMAWLVLDGSHPNQKLLPPPSDLPKC |
| Enzyme Length | 579 |
| Uniprot Accession Number | Q5N9X2 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=4 hydroquinone + O2 = 4 benzosemiquinone + 2 H2O; Xref=Rhea:RHEA:11276, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:17594, ChEBI:CHEBI:17977; EC=1.10.3.2; |
| DNA Binding | |
| EC Number | 1.10.3.2 |
| Enzyme Function | FUNCTION: Lignin degradation and detoxification of lignin-derived products. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Domain (3); Erroneous initiation (1); Glycosylation (15); Metal binding (11); Signal peptide (1) |
| Keywords | Apoplast;Copper;Glycoprotein;Lignin degradation;Metal-binding;Oxidoreductase;Reference proteome;Repeat;Secreted;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted, extracellular space, apoplast {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..28; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 63,052 |
| Kinetics | |
| Metal Binding | METAL 86; /note=Copper 1; /evidence=ECO:0000250; METAL 88; /note=Copper 2; /evidence=ECO:0000250; METAL 131; /note=Copper 2; /evidence=ECO:0000250; METAL 133; /note=Copper 3; /evidence=ECO:0000250; METAL 480; /note=Copper 4; /evidence=ECO:0000250; METAL 483; /note=Copper 1; /evidence=ECO:0000250; METAL 485; /note=Copper 3; /evidence=ECO:0000250; METAL 542; /note=Copper 3; /evidence=ECO:0000250; METAL 543; /note=Copper 4; /evidence=ECO:0000250; METAL 544; /note=Copper 2; /evidence=ECO:0000250; METAL 548; /note=Copper 4; /evidence=ECO:0000250 |
| Rhea ID | RHEA:11276 |
| Cross Reference Brenda |