| IED ID | IndEnz0015000049 |
| Enzyme Type ID | laccase000049 |
| Protein Name |
Laccase-18 EC 1.10.3.2 Benzenediol:oxygen oxidoreductase 18 Diphenol oxidase 18 Urishiol oxidase 18 |
| Gene Name | LAC18 Os11g0264000 LOC_Os11g16260 OsJ_032226 |
| Organism | Oryza sativa subsp. japonica (Rice) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae Liliopsida Petrosaviidae commelinids Poales Poaceae BOP clade Oryzoideae Oryzeae Oryzinae Oryza Oryza sativa (Rice) Oryza sativa subsp. japonica (Rice) |
| Enzyme Sequence | MEKLSTAASLFCVVVAATALAMAVVGGEAAVVEQTFMVHEMNVTHLCNTTKIYVVNGRFPGPTVDVTEGDTVVVHVINRLPHGLTIHWHGVRQMRSCWADGAGYVTECPIHPGGEKTYRFNVTGQVGTLWWHAHVTCLRATINGAFIIRPRNGKYPFLTPAKDVPIIIGEWWELDLIELDRRMLDGNFDDNPLSATINGKLGDLSNCSSTVEESFVLDVKRGESYLLRVINTALFSEYYFKVAGHTFTVVGADGNYLTPYKTDMVTVAPGEAIDVLMFTDAPPAYYHMVALANQPPPPDLQIPQLTSRGLIRYAGAAMDSNNLPMPMPVMPDQHNTMPSYYFRRNLTGLALPEQQQRHRVPAHVDERLLITLGLGSICRGGNTTTCKRGRSPETVVVATMNNVSFHHTNATALLEHYYDGRPEGVYTEDFPVRPPRPFNYTDRELIPAGPLEAALEPTAKAMRLRRFRYNASVEIVFQSTTLLQSDSNPMHLHGYDVFVLAQGLGNFDPKRDVEKFNYHNPQLRNTVQVPRGGWAAVRFLADNPGMWYLHCHFEFHIIMGMATAFIVEDGPTPETSLPPPPPEFKRCGTNGLSQP |
| Enzyme Length | 595 |
| Uniprot Accession Number | Q53LU4 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=4 hydroquinone + O2 = 4 benzosemiquinone + 2 H2O; Xref=Rhea:RHEA:11276, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:17594, ChEBI:CHEBI:17977; EC=1.10.3.2; |
| DNA Binding | |
| EC Number | 1.10.3.2 |
| Enzyme Function | FUNCTION: Lignin degradation and detoxification of lignin-derived products. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Domain (3); Erroneous gene model prediction (1); Glycosylation (10); Metal binding (12); Region (1); Signal peptide (1) |
| Keywords | Apoplast;Copper;Glycoprotein;Lignin degradation;Metal-binding;Oxidoreductase;Reference proteome;Repeat;Secreted;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted, extracellular space, apoplast {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..29; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 66,189 |
| Kinetics | |
| Metal Binding | METAL 87; /note=Copper 1; /evidence=ECO:0000250; METAL 89; /note=Copper 2; /evidence=ECO:0000250; METAL 132; /note=Copper 2; /evidence=ECO:0000250; METAL 134; /note=Copper 3; /evidence=ECO:0000250; METAL 488; /note=Copper 4; /evidence=ECO:0000255; METAL 491; /note=Copper 1; /evidence=ECO:0000250; METAL 493; /note=Copper 3; /evidence=ECO:0000250; METAL 550; /note=Copper 3; /evidence=ECO:0000250; METAL 551; /note=Copper 4; /evidence=ECO:0000255; METAL 552; /note=Copper 2; /evidence=ECO:0000250; METAL 556; /note=Copper 4; /evidence=ECO:0000255; METAL 561; /note=Copper 4; /evidence=ECO:0000255 |
| Rhea ID | RHEA:11276 |
| Cross Reference Brenda |