| IED ID | IndEnz0015000078 |
| Enzyme Type ID | laccase000078 |
| Protein Name |
Laccase-12 EC 1.10.3.2 Benzenediol:oxygen oxidoreductase 12 Diphenol oxidase 12 Urishiol oxidase 12 |
| Gene Name | LAC12 Os05g0458500 LOC_Os05g38410 OJ1362_D02.9 OsJ_018046 |
| Organism | Oryza sativa subsp. japonica (Rice) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae Liliopsida Petrosaviidae commelinids Poales Poaceae BOP clade Oryzoideae Oryzeae Oryzinae Oryza Oryza sativa (Rice) Oryza sativa subsp. japonica (Rice) |
| Enzyme Sequence | MAAASSVLRCCLLVAALMTLSAMGAEAITRQYLFDVQTTSVTRLCSTKSIVTVNGQYPGPTLFAREGDHVEVTVVNHSPYNMSIHWHGIRQLLSGWADGPSYITQCPIQPGGSYVYRFTITGQRGTLWWHAHISWLRATVHGPMVILPPAGVGYPFPAPHEEVPIMFGEWWNNDTEAVISQALQTGGGPNISDAYTLNGLPGPLYNCSAQDTFKLKVKPGKTYMLRLINAALNDELFFSIANHTLTVVDVDALYVKPFTVDTLIIAPGQTSNVLLTAKPTYPGASYYMLARPYTTTQGTFDNTTVAGVLEYDDPCPTTAAGKIVPIFSPTLPQINDTNAVSNFTAKLRSLASAGYPAAVPQQVDHRFFFTVGLGTHPCAVNGTCQGPNGSRFAASINNVSFVLPATALLQSHFAGKSKGVYASNFPYYPLNPFNYTGTPPNNTNVMNGTKVLVLPYGANVELVMQDTSILGAESHPLHLHGFNFFVVGQGFGNFDPINDPAKFNLYDPVERNTVGVPAGGWVAIRFHADNPGVWFMHCHLEVHMSWGLKMAWLVLDGSRPDQKLPPPPLDLPKC |
| Enzyme Length | 574 |
| Uniprot Accession Number | B9FJH4 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=4 hydroquinone + O2 = 4 benzosemiquinone + 2 H2O; Xref=Rhea:RHEA:11276, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:17594, ChEBI:CHEBI:17977; EC=1.10.3.2; |
| DNA Binding | |
| EC Number | 1.10.3.2 |
| Enzyme Function | FUNCTION: Lignin degradation and detoxification of lignin-derived products. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Domain (3); Erroneous gene model prediction (3); Glycosylation (14); Metal binding (11); Signal peptide (1) |
| Keywords | Apoplast;Copper;Glycoprotein;Lignin degradation;Metal-binding;Oxidoreductase;Reference proteome;Repeat;Secreted;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted, extracellular space, apoplast {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..27; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 62,348 |
| Kinetics | |
| Metal Binding | METAL 85; /note=Copper 1; /evidence=ECO:0000250; METAL 87; /note=Copper 2; /evidence=ECO:0000250; METAL 130; /note=Copper 2; /evidence=ECO:0000250; METAL 132; /note=Copper 3; /evidence=ECO:0000250; METAL 475; /note=Copper 4; /evidence=ECO:0000250; METAL 478; /note=Copper 1; /evidence=ECO:0000250; METAL 480; /note=Copper 3; /evidence=ECO:0000250; METAL 537; /note=Copper 3; /evidence=ECO:0000250; METAL 538; /note=Copper 4; /evidence=ECO:0000250; METAL 539; /note=Copper 2; /evidence=ECO:0000250; METAL 543; /note=Copper 4; /evidence=ECO:0000250 |
| Rhea ID | RHEA:11276 |
| Cross Reference Brenda |