| IED ID | IndEnz0015000107 |
| Enzyme Type ID | laccase000107 |
| Protein Name |
Laccase-8 EC 1.10.3.2 Benzenediol:oxygen oxidoreductase 8 Diphenol oxidase 8 Urishiol oxidase 8 |
| Gene Name | LAC8 Os01g0850800 LOC_Os01g63200 P0529H11.24 |
| Organism | Oryza sativa subsp. japonica (Rice) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae Liliopsida Petrosaviidae commelinids Poales Poaceae BOP clade Oryzoideae Oryzeae Oryzinae Oryza Oryza sativa (Rice) Oryza sativa subsp. japonica (Rice) |
| Enzyme Sequence | MASAAMLVPLVLVLCTAAASAAVVEHTFKVGGTKITQLCMNSVIYTANQQLPGPTIEVTEGDTLVVHAVNDSPYPLSLHWHGVYQLRSGWNDGANKITQCPIQPSGNFTYRFNITGQEGTLWWHAHSSLLRATIYGALIIKPRNGPSGYPFPEPYEEIPILLGEWWNRNVDDVENDGYLTGLGPQISDALTINGMPGDQNRCKGSAMYEVEVEYGKTCLLRIINAAVNVELFFKVAGHTFTVVAADASYTKPYATDVIVIAPGQTVDALMNTTASPGRYYMAAHVFDSKTVAVPFDQSTATGIVKYKGVPNYAPAAMPSLPPHDDVVTAGRFYWSLTGLARPSDPGVPTTVDHNMVVTFGLDQAPCAPNQTKCSGFALVAAMNRNSFQFPDQKVSLLEALYKGVPGVYSEDFPDFPPPMQGFRKATAVKKVKYNDVVEVVLQSEQYSSTLGTENHPIHLHGFDFYLLAQGLGRFNPSMKSKYNLVDPQVRNTVAVPAGGWAVIRFMANNPGMWFMHCHLDAHLPLGLAMVFEVLNGPAPNLLPPPPVDHPKCHG |
| Enzyme Length | 554 |
| Uniprot Accession Number | Q0JHP8 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=4 hydroquinone + O2 = 4 benzosemiquinone + 2 H2O; Xref=Rhea:RHEA:11276, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:17594, ChEBI:CHEBI:17977; EC=1.10.3.2; |
| DNA Binding | |
| EC Number | 1.10.3.2 |
| Enzyme Function | FUNCTION: Lignin degradation and detoxification of lignin-derived products. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Domain (3); Erroneous gene model prediction (1); Glycosylation (4); Metal binding (11); Signal peptide (1) |
| Keywords | Apoplast;Copper;Glycoprotein;Lignin degradation;Metal-binding;Oxidoreductase;Reference proteome;Repeat;Secreted;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted, extracellular space, apoplast {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..21; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 60,278 |
| Kinetics | |
| Metal Binding | METAL 79; /note=Copper 1; /evidence=ECO:0000250; METAL 81; /note=Copper 2; /evidence=ECO:0000250; METAL 124; /note=Copper 2; /evidence=ECO:0000250; METAL 126; /note=Copper 3; /evidence=ECO:0000250; METAL 455; /note=Copper 4; /evidence=ECO:0000250; METAL 458; /note=Copper 1; /evidence=ECO:0000250; METAL 460; /note=Copper 3; /evidence=ECO:0000250; METAL 516; /note=Copper 3; /evidence=ECO:0000250; METAL 517; /note=Copper 4; /evidence=ECO:0000250; METAL 518; /note=Copper 2; /evidence=ECO:0000250; METAL 522; /note=Copper 4; /evidence=ECO:0000250 |
| Rhea ID | RHEA:11276 |
| Cross Reference Brenda |