| IED ID | IndEnz0015000119 |
| Enzyme Type ID | laccase000119 |
| Protein Name |
Laccase ARB_05828 EC 1.10.3.2 Benzenediol:oxygen oxidoreductase ARB_05828 Diphenol oxidase ARB_05828 Urishiol oxidase ARB_05828 |
| Gene Name | ARB_05828 |
| Organism | Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Onygenales Arthrodermataceae (dermatophytes) Trichophyton Arthroderma benhamiae (Trichophyton mentagrophytes) Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes) |
| Enzyme Sequence | MKRLGLAALYIGSALAWPEPHGPPSRNVPRDDFPMFNPLPSTDLNTRLIRCEYPSMKGWTYSNKKNGDWLKYVGSKPGEITEYNIDTDNDKYVPQGITRKYHLEVTDESVNMDGTMFDQAKVFNKQYPGPWIQITVTNKLKHNGTAIHWHGIRMMENMFNDGVPGVTQCPIPPGSSMTYRFKASQYGSSWYHSHYSLQYADGLFGPMTIHGPTSAGYDKAVDPLLMTDHLHSSAFEEYHKELEGKPPAMDSIILNGKGDYDQTGDLKKKYRTVLKPGKKYLLRLINTSVATTFVFSIDGHKFQVVGSDFVPIEPYVTDHIAVGIGQRYHVILEGLSEEEAKKNGRYWVRTTPAKGCSKFAPGRGTDDRTGVIYYNKDDGVSPTTEIGAFSLDCRDEPLEKLVPKVKWTVPDPGLNMVGAFEKPADVQLGKWHRPGYPDTDNLVSNWEFGPSPMWINYSEPIIKNLDKDSFPSTWVVYPADDYVNDKWVYLVITGKKLKPLSSQVAVAHPIHLHGHDFVLLQQSMEPWDSTEVNLKLDNPPRREVTLLPAGGFIVIAFKPDNPGSWLLHCHIAWHASAGLALQVLERKEDLKALTLNNPDFDFMQENCRKWDAWHSDKTNYWNPSGHFQDDSGV |
| Enzyme Length | 633 |
| Uniprot Accession Number | D4APX3 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=4 hydroquinone + O2 = 4 benzosemiquinone + 2 H2O; Xref=Rhea:RHEA:11276, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:17594, ChEBI:CHEBI:17977; EC=1.10.3.2; Evidence={ECO:0000250|UniProtKB:Q70KY3}; |
| DNA Binding | |
| EC Number | 1.10.3.2 |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Disulfide bond (1); Domain (1); Glycosylation (3); Metal binding (11); Propeptide (1); Signal peptide (1) |
| Keywords | Copper;Disulfide bond;Glycoprotein;Metal-binding;Oxidoreductase;Reference proteome;Secreted;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:21919205}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..16; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 71,552 |
| Kinetics | |
| Metal Binding | METAL 148; /note=Copper 1; type 2; /evidence=ECO:0000250|UniProtKB:D0VWU3; METAL 150; /note=Copper 2; type 3; /evidence=ECO:0000250|UniProtKB:D0VWU3; METAL 192; /note=Copper 2; type 3; /evidence=ECO:0000250|UniProtKB:D0VWU3; METAL 194; /note=Copper 3; type 3; /evidence=ECO:0000250|UniProtKB:D0VWU3; METAL 508; /note=Copper 4; type 1; /evidence=ECO:0000250|UniProtKB:D0VWU3; METAL 511; /note=Copper 1; type 2; /evidence=ECO:0000250|UniProtKB:D0VWU3; METAL 513; /note=Copper 3; type 3; /evidence=ECO:0000250|UniProtKB:D0VWU3; METAL 568; /note=Copper 3; type 3; /evidence=ECO:0000250|UniProtKB:D0VWU3; METAL 569; /note=Copper 4; type 1; /evidence=ECO:0000250|UniProtKB:D0VWU3; METAL 570; /note=Copper 2; type 3; /evidence=ECO:0000250|UniProtKB:D0VWU3; METAL 574; /note=Copper 4; type 1; /evidence=ECO:0000250|UniProtKB:D0VWU3 |
| Rhea ID | RHEA:11276 |
| Cross Reference Brenda |