| IED ID | IndEnz0015000164 |
| Enzyme Type ID | laccase000164 |
| Protein Name |
Laccase-6 EC 1.10.3.2 Benzenediol:oxygen oxidoreductase 6 Diphenol oxidase 6 Urishiol oxidase 6 |
| Gene Name | LAC6 At2g46570 F13A10.10 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress) |
| Enzyme Sequence | MTSSAVPSLFRLSFLLFTLQVMNIGRIGAATRFYQFKVQTIRLTRLCQTNEIVTVNKKFPGPAISAQEDDRIVIKVINMTPYNTTIHWHGIKQKRSCWYDGPSYITQCPIQSGQSFTYNFKVAQQKGTFLWHAHFSWLRATVYGPLIVYPKASVPYPFKKPFNEHTILLGEYWLKNVVELEQHVLESGGPPPPADAFTINGQPGPNYNCSSKDVYEIQIVPRKIYLLRLINAGINMETFFTIANHRLTIVEVDGEYTKPYTTERVMLVPGQTMNILVTADQTVGRYSMAMGPYESAKNVKFQNTSAIANFQYIGALPNNVTVPAKLPIFNDNIAVKTVMDGLRSLNAVDVPRNIDAHLFITIGLNVNKCNSENPNNKCQGPRKGRLAASMNNISFIEPKVSILEAYYKQLEGYFTLDFPTTPEKAYDFVNGAPNDIANDTQAANGTRAIVFEYGSRIQIIFQNTGTLTTENHPIHLHGHSFYVIGYGTGNYDQQTAKFNLEDPPYLNTIGVPVGGWAAIRFVANNPGLWLLHCHFDIHQTWGMSTMFIVKNGKKVQESLPHPPADLPKC |
| Enzyme Length | 569 |
| Uniprot Accession Number | Q9ZPY2 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=4 hydroquinone + O2 = 4 benzosemiquinone + 2 H2O; Xref=Rhea:RHEA:11276, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:17594, ChEBI:CHEBI:17977; EC=1.10.3.2; |
| DNA Binding | |
| EC Number | 1.10.3.2 |
| Enzyme Function | FUNCTION: Lignin degradation and detoxification of lignin-derived products. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Alternative sequence (3); Chain (1); Domain (3); Glycosylation (7); Metal binding (12); Signal peptide (1) |
| Keywords | Alternative splicing;Apoplast;Copper;Glycoprotein;Lignin degradation;Metal-binding;Oxidoreductase;Reference proteome;Repeat;Secreted;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted, extracellular space, apoplast {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..29; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 16243908; 21447792; 9914531; |
| Motif | |
| Gene Encoded By | |
| Mass | 63,901 |
| Kinetics | |
| Metal Binding | METAL 87; /note=Copper 1; type 2; /evidence=ECO:0000250; METAL 89; /note=Copper 2; type 3; /evidence=ECO:0000250; METAL 132; /note=Copper 2; type 3; /evidence=ECO:0000250; METAL 134; /note=Copper 3; type 3; /evidence=ECO:0000250; METAL 472; /note=Copper 4; type 1; /evidence=ECO:0000250; METAL 475; /note=Copper 1; type 2; /evidence=ECO:0000250; METAL 477; /note=Copper 3; type 3; /evidence=ECO:0000250; METAL 532; /note=Copper 3; type 3; /evidence=ECO:0000250; METAL 533; /note=Copper 4; type 1; /evidence=ECO:0000250; METAL 534; /note=Copper 2; type 3; /evidence=ECO:0000250; METAL 538; /note=Copper 4; type 1; /evidence=ECO:0000250; METAL 543; /note=Copper 4; type 1; /evidence=ECO:0000250 |
| Rhea ID | RHEA:11276 |
| Cross Reference Brenda |