| IED ID |
IndEnz0016000045 |
| Enzyme Type ID |
tyrosinase000045 |
| Protein Name |
Hemocyanin A chain
|
| Gene Name |
|
| Organism |
Panulirus interruptus (California spiny lobster) (Palinurus interruptus) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Metazoa
Eumetazoa
Bilateria
Protostomia
Ecdysozoa
Panarthropoda
Arthropoda
Mandibulata
Pancrustacea
Crustacea
Multicrustacea
Malacostraca
Eumalacostraca
Eucarida
Decapoda
Pleocyemata
Achelata
Palinuroidea
Palinuridae (spiny lobsters)
Panulirus
Panulirus interruptus (California spiny lobster) (Palinurus interruptus)
|
| Enzyme Sequence |
DALGTGNAQKQQDINHLLDKIYEPTKYPDLKEIAENFNPLGDTSIYNDHGAAVETLMKELNDHRLLEQRHWYSLFNTRQRKEALMLFAVLNQCKEWYCFRSNAAYFRERMNEGEFVYALYVSVIHSKLGDGIVLPPLYQITPHMFTNSEVIDKAYSAKMTQKQGTFNVSFTGTKKNREQRVAYFGEDIGMNIHHVTWHMDFPFWWEDSYGYHLDRKGELFFWVHHQLTARFDFERLSNWLDPVDELHWDRIIREGFAPLTSYKYGGEFPVRPDNIHFEDVDGVAHVHDLEITESRIHEAIDHGYITDSDGHTIDIRQPKGIELLGDIIESSKYSSNVQYYGSLHNTAHVMLGRQGDPHGKFNLPPGVMEHFETATRDPSFFRLHKYMDNIFKKHTDSFPPYTHDNLEFSGMVVNGVAIDGELITFFDEFQYSLINAVDSGENIEDVEINARVHRLNHKEFTYKITMSNNNDGERLATFRIFLCPIEDNNGITLTLDEARWFCIELDKFFQKVPKGPETIERSSKDSSVTVPDMPSFQSLKEQADNAVNGGHDLDLSAYERSCGIPDRMLLPKSKPEGMEFNLYVAVTDGDKDTEGHNGGHDYGGTHAQCGVHGEAYPDNRPLGYPLERRIPDERVIDGVSNIKHVVVKIVHHLEHHD |
| Enzyme Length |
657 |
| Uniprot Accession Number |
P04254 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Hemocyanins are copper-containing oxygen carriers occurring freely dissolved in the hemolymph of many mollusks and arthropods. {ECO:0000269|PubMed:2585484, ECO:0000269|Ref.6}. |
| Temperature Dependency |
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| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Beta strand (27); Chain (1); Disulfide bond (3); Glycosylation (1); Helix (26); Metal binding (6); Region (1); Turn (12) |
| Keywords |
3D-structure;Copper;Direct protein sequencing;Disulfide bond;Glycoprotein;Metal-binding;Oxygen transport;Secreted;Transport |
| Interact With |
|
| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Secreted, extracellular space {ECO:0000269|PubMed:3208765}. |
| Modified Residue |
|
| Post Translational Modification |
|
| Signal Peptide |
|
| Structure 3D |
X-ray crystallography (2) |
| Cross Reference PDB |
1HC1;
1HCY;
|
| Mapped Pubmed ID |
- |
| Motif |
|
| Gene Encoded By |
|
| Mass |
75,696 |
| Kinetics |
|
| Metal Binding |
METAL 194; /note="Copper A"; /evidence="ECO:0000269|PubMed:2585484, ECO:0007744|PDB:1HC1, ECO:0007744|PDB:1HCY"; METAL 198; /note="Copper A"; /evidence="ECO:0000269|PubMed:2585484, ECO:0007744|PDB:1HC1, ECO:0007744|PDB:1HCY"; METAL 224; /note="Copper A"; /evidence="ECO:0000269|PubMed:2585484, ECO:0007744|PDB:1HC1, ECO:0007744|PDB:1HCY"; METAL 344; /note="Copper B"; /evidence="ECO:0000269|PubMed:2585484, ECO:0007744|PDB:1HC1, ECO:0007744|PDB:1HCY"; METAL 348; /note="Copper B"; /evidence="ECO:0000269|PubMed:2585484, ECO:0007744|PDB:1HC1, ECO:0007744|PDB:1HCY"; METAL 384; /note="Copper B"; /evidence="ECO:0000269|PubMed:2585484, ECO:0007744|PDB:1HC1, ECO:0007744|PDB:1HCY" |
| Rhea ID |
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| Cross Reference Brenda |
|