| IED ID |
IndEnz0016000109 |
| Enzyme Type ID |
tyrosinase000109 |
| Protein Name |
Hemocyanin II
|
| Gene Name |
|
| Organism |
Limulus polyphemus (Atlantic horseshoe crab) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Metazoa
Eumetazoa
Bilateria
Protostomia
Ecdysozoa
Panarthropoda
Arthropoda
Chelicerata
Merostomata (horseshoe crabs)
Xiphosura
Limulidae
Limulus
Limulus polyphemus (Atlantic horseshoe crab)
|
| Enzyme Sequence |
TLHDKQIRVCHLFEQLSSATVIGDGDKHKHSDRLKNVGKLQPGAIFSCFHPDHLEEARHLYEVFWEAGDFNDFIEIAKEARTFVNEGLFAFAAEVAVLHRDDCKGLYVPPVQEIFPDKFIPSAAINEAFKKAHVRPEFDESPILVDVQDTGNILDPEYRLAYYREDVGINAHHWHWHLVYPSTWNPKYFGKKKDRKGELFYYMHQQMCARYDCERLSNGMHRMLPFNNFDEPLAGYAPHLTHVASGKYYSPRPDGLKLRDLGDIEISEMVRMRERILDSIHLGYVISEDGSHKTLDELHGTDILGALVESSYESVNHEYYGNLHNWGHVTMARIHDPDGRFHEEPGVMSDTSTSLRDPIFYNWHRFIDNIFHEYKNTLKPYDHDVLNFPDIQVQDVTLHARVDNVVHFTMREQELELKHGINPGNARSIKARYYHLDHEPFSYAVNVQNNSASDKHATVRIFLAPKYDELGNEIKADELRRTAIELDKFKTDLHPGKNTVVRHSLDSSVTLSHQPTFEDLLHGVGLNEHKSEYCSCGWPSHLLVPKGNIKGMEYHLFVMLTDWDKDKVDGSESVACVDAVSYCGARDHKYPDKKPMGFPFDRPIHTEHISDFLTNNMFIKDIKIKFHE |
| Enzyme Length |
628 |
| Uniprot Accession Number |
P04253 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Hemocyanins are copper-containing oxygen carriers occurring freely dissolved in the hemolymph of many mollusks and arthropods. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Beta strand (20); Chain (1); Disulfide bond (2); Glycosylation (1); Helix (30); Metal binding (6); Modified residue (1); Turn (7) |
| Keywords |
3D-structure;Copper;Direct protein sequencing;Disulfide bond;Glycoprotein;Metal-binding;Oxygen transport;Secreted;Transport |
| Interact With |
|
| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Secreted, extracellular space. |
| Modified Residue |
MOD_RES 1; /note=Blocked amino end (Thr); partial; /evidence=ECO:0000269|PubMed:3525550 |
| Post Translational Modification |
|
| Signal Peptide |
|
| Structure 3D |
X-ray crystallography (4) |
| Cross Reference PDB |
1LL1;
1LLA;
1NOL;
1OXY;
|
| Mapped Pubmed ID |
7984626;
|
| Motif |
|
| Gene Encoded By |
|
| Mass |
72,629 |
| Kinetics |
|
| Metal Binding |
METAL 173; /note=Copper 1; /evidence=ECO:0000269|PubMed:8518732; METAL 177; /note=Copper 1; /evidence=ECO:0000269|PubMed:8518732; METAL 204; /note=Copper 1; /evidence=ECO:0000269|PubMed:8518732; METAL 324; /note=Copper 2; /evidence=ECO:0000269|PubMed:8518732; METAL 328; /note=Copper 2; /evidence=ECO:0000269|PubMed:8518732; METAL 364; /note=Copper 2; /evidence=ECO:0000269|PubMed:8518732 |
| Rhea ID |
|
| Cross Reference Brenda |
|