| IED ID | IndEnz0016000158 |
| Enzyme Type ID | tyrosinase000158 |
| Protein Name |
Putative synaptotagmin-14-like protein Synaptotagmin XIV protein pseudogene 1 Synaptotagmin XIV-derived protein Synaptotagmin XIV-like protein |
| Gene Name | SYT14P1 SYT14L SYT14LP1 SYTDEP |
| Organism | Homo sapiens (Human) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Primates Haplorrhini Simiiformes Catarrhini Hominoidea (apes) Hominidae (great apes) Homininae Homo Homo sapiens (Human) |
| Enzyme Sequence | MLEGFQILVQNTVQGTIHKIKCVCDSQMSVSEMSCSESTSACQSLEDGSVPEILISLLYNATNGRLSAEVIKGSHLKNWAANRPPNTYVKLTLRKSTDQEMSKCKISIRRGRPNPVYKETFVFKVTLFQLSHVTLMLSVYNKSSMRRKMIGWIYLGLNSSGEELNHWTEMKESKGRQVRRWQALLESR |
| Enzyme Length | 188 |
| Uniprot Accession Number | Q58G82 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Plays a role in melanocyte differentiation; enhances dendrite outgrowth, melanin content and tyrosinase activity through the modulation of ERK and/or CREB pathways (PubMed:23999003). {ECO:0000269|PubMed:16376304, ECO:0000269|PubMed:23999003}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Domain (1); Natural variant (1) |
| Keywords | Differentiation;Reference proteome |
| Interact With | |
| Induction | INDUCTION: Up-regulated during neutrophil differentiation (PubMed:16376304). {ECO:0000269|PubMed:16376304}. |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 21,436 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |