Detail Information for IndEnz0016000213
IED ID IndEnz0016000213
Enzyme Type ID tyrosinase000213
Protein Name Tyrosine phenol-lyase
EC 4.1.99.2
Beta-tyrosinase
Gene Name tpl Npun_R5724
Organism Nostoc punctiforme (strain ATCC 29133 / PCC 73102)
Taxonomic Lineage cellular organisms Bacteria Terrabacteria group Cyanobacteria/Melainabacteria group Cyanobacteria Nostocales Nostocaceae Nostoc Nostoc punctiforme Nostoc punctiforme (strain ATCC 29133 / PCC 73102)
Enzyme Sequence MTDAKQTSPRRRRSWAEPYKIKVVEPLKITTRAEREQAIAQAGYNTFLLRSEDVYIDLLTDSGTSAMSDYQWAGMMLGDEAYAGSKNFYNLEASIQKYYGYRHIVPTHQGRGAENILSQILIKPGDYIPGNMYFTTTRLHQELAGGTFVDVIIDEAHDAQSLHPFKGNVDLQKLTDLIERVGAERIPYISVAGTVNMAGGQPISMANLRAVHQLAQTYGIRIILDATRAVENAHFIQQREEDYSSQAIATILREFCSYTDGCTMSGKKDALVNIGGWLALNDYNLYEEARNLIVIYEGLHTYGGMAGRDMEAMARGIEESVQDDHIRARVGQVEYLGQKLLDWGIPIVVPIGGHAIYLDAKRFLPQIPQDQFPAQRLAAELYLEAGIRAMERGIVSAGRNKETGDNYYPELELVRLTIPRRVYTQAHMDLTAEAVEEVYHNRDRLRGLKMIYEPKYLRFFQARFELQ
Enzyme Length 467
Uniprot Accession Number B2J908
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=H2O + L-tyrosine = NH4(+) + phenol + pyruvate; Xref=Rhea:RHEA:21704, ChEBI:CHEBI:15361, ChEBI:CHEBI:15377, ChEBI:CHEBI:15882, ChEBI:CHEBI:28938, ChEBI:CHEBI:58315; EC=4.1.99.2; Evidence={ECO:0000255|HAMAP-Rule:MF_00543};
DNA Binding
EC Number 4.1.99.2
Enzyme Function
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Modified residue (1)
Keywords Lyase;Pyridoxal phosphate;Reference proteome
Interact With
Induction
Subcellular Location
Modified Residue MOD_RES 268; /note=N6-(pyridoxal phosphate)lysine; /evidence=ECO:0000255|HAMAP-Rule:MF_00543
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 52,890
Kinetics
Metal Binding
Rhea ID RHEA:21704
Cross Reference Brenda