| IED ID | IndEnz0017000017 |
| Enzyme Type ID | manganese peroxidase000017 |
| Protein Name |
Low-redox potential peroxidase EC 1.11.1.7 Putative ligninolytic peroxidase |
| Gene Name | LnP |
| Organism | Taiwanofungus camphoratus (Poroid brown-rot fungus) (Antrodia camphorata) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Basidiomycota Agaricomycotina Agaricomycetes Agaricomycetes incertae sedis Polyporales Polyporales incertae sedis Taiwanofungus Taiwanofungus camphoratus (Poroid brown-rot fungus) (Antrodia camphorata) |
| Enzyme Sequence | MRSSTHIFVSFVVYCGVFVTSAIALSNHTNAYQCDRWSNVLNELQANLFHEGQCRSAALRASGTFGGGGADGSIIQFAHTELAYPANEGLEEMVYTLKHFADGHEVSYGDMIQFAGAVALSNCPGSPRLRFYAGRPEAIAPSPPNLLPLPTDPVEKILSRMADAGFNAGDTVALLAAHSIAVQNTIDPSIPDSPLDSTPRIFDTQFYLETLLRGTRYPGKGRGPAQSKSPIEHEFRLASDAAIARHTSTACEWQSFIDNQEGLRSAFRNAMVKLANQGHDNLVDCSFVIPVPPPWNLPVEYPSGKSRSDVEQSCSDVPFPTISLNSDVHD |
| Enzyme Length | 330 |
| Uniprot Accession Number | C0IW58 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O; Xref=Rhea:RHEA:56136, ChEBI:CHEBI:15377, ChEBI:CHEBI:16240, ChEBI:CHEBI:139520, ChEBI:CHEBI:139521; EC=1.11.1.7; |
| DNA Binding | |
| EC Number | 1.11.1.7 |
| Enzyme Function | FUNCTION: Can oxidize the lignin redox mediator veratryl alcohol to veratryl aldehyde. May be involved in oxidation of lignocellulose substrates. {ECO:0000269|PubMed:19202090}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Disulfide bond (3); Glycosylation (1); Metal binding (8); Sequence conflict (3); Signal peptide (1) |
| Keywords | Calcium;Disulfide bond;Glycoprotein;Heme;Hydrogen peroxide;Iron;Metal-binding;Oxidoreductase;Peroxidase;Secreted;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000255|PROSITE-ProRule:PRU00297, ECO:0000269|PubMed:19202090}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..24; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 35,770 |
| Kinetics | BIOPHYSICOCHEMICAL PROPERTIES: Kinetic parameters: KM=13.1 uM for veratryl alcohol {ECO:0000269|PubMed:19202090}; |
| Metal Binding | METAL 69; /note=Calcium 1; via carbonyl oxygen; /evidence=ECO:0000255|PROSITE-ProRule:PRU00297; METAL 71; /note=Calcium 1; /evidence=ECO:0000255|PROSITE-ProRule:PRU00297; METAL 73; /note=Calcium 1; /evidence=ECO:0000255|PROSITE-ProRule:PRU00297; METAL 178; /note=Iron (heme b axial ligand); /evidence=ECO:0000255|PROSITE-ProRule:PRU00297; METAL 179; /note=Calcium 2; /evidence=ECO:0000255|PROSITE-ProRule:PRU00297; METAL 196; /note=Calcium 2; /evidence=ECO:0000255|PROSITE-ProRule:PRU00297; METAL 198; /note=Calcium 2; /evidence=ECO:0000255|PROSITE-ProRule:PRU00297; METAL 203; /note=Calcium 2; /evidence=ECO:0000255|PROSITE-ProRule:PRU00297 |
| Rhea ID | RHEA:56136 |
| Cross Reference Brenda |