| IED ID |
IndEnz0018000044 |
| Enzyme Type ID |
peroxidase000044 |
| Protein Name |
Ankyrin repeat domain-containing protein 2B
|
| Gene Name |
AKR2B At2g17390 F5J6.15 |
| Organism |
Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Viridiplantae
Streptophyta
Streptophytina
Embryophyta
Tracheophyta
Euphyllophyta
Spermatophyta
Magnoliopsida
Mesangiospermae
eudicotyledons
Gunneridae
Pentapetalae
rosids
malvids
Brassicales
Brassicaceae
Camelineae
Arabidopsis
Arabidopsis thaliana (Mouse-ear cress)
|
| Enzyme Sequence |
MASSSEKTPLIPSDEKNDTKEESKSTTKPESGSGAPPSPSPTDPGLDFNAFDFSGMAGILNDPSIKELAEQIAKDPSFNQLAEQLQRSVPTGSHEGGLPNFDPQQYMQTMQQVMENPEFRTMAERLGNALVQDPQMSPFLEALGNPAASEQFAERMAQMKEDPELKPILAEIDAGGPSAMMKYWNDKDVLAKLGEAMGIAVGADQTVAAEPEEAEEGEEEESIVHQTASLGDVEGLKAALASGGNKDEEDSEGRTALHFACGYGEVRCAQVLLDAGANANAIDKNKNTPLHYAAGYGRKECVSLLLENGAAVTQQNMDNKNPIDVARLNNQLDVVKLLEKDAFL |
| Enzyme Length |
344 |
| Uniprot Accession Number |
Q29Q26 |
| Absorption |
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| Active Site |
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| Activity Regulation |
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| Binding Site |
BINDING 225; /note=Monogalactosyldiacylglycerol (MGDG); /evidence=ECO:0000250|UniProtKB:Q9SAR5; BINDING 248; /note=Monogalactosyldiacylglycerol (MGDG); /evidence=ECO:0000250|UniProtKB:Q9SAR5; BINDING 296; /note=Phosphatidylglycerol (PG); /evidence=ECO:0000250|UniProtKB:Q9SAR5; BINDING 298; /note=Phosphatidylglycerol (PG); /evidence=ECO:0000250|UniProtKB:Q9SAR5 |
| Calcium Binding |
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| catalytic Activity |
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| DNA Binding |
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| EC Number |
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| Enzyme Function |
FUNCTION: Exhibits chaperone activity toward chloroplast outer envelope membrane, mitochondrion outer membrane, endoplasmic reticulum membrane and peroxisomal proteins, by recruiting specific proteins containing a single transmembrane associated with an AKR2A-binding sequence (ABS) and subsequently binding glycolipids (e.g. monogalactosyldiacylglycerol (MGDG) and phosphatidylglycerol (PG)) present in the membrane of the target organelle. {ECO:0000250|UniProtKB:Q9SAR5}. |
| Temperature Dependency |
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| PH Dependency |
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| Pathway |
|
| nucleotide Binding |
|
| Features |
Binding site (4); Chain (1); Compositional bias (1); Region (1); Repeat (4) |
| Keywords |
ANK repeat;Chaperone;Chloroplast;Cytoplasm;Lipid-binding;Membrane;Nucleus;Plastid;Plastid outer membrane;Reference proteome;Repeat |
| Interact With |
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| Induction |
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| Subcellular Location |
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9SAR5}. Nucleus {ECO:0000250|UniProtKB:Q9SAR5}. Plastid, chloroplast outer membrane {ECO:0000250|UniProtKB:Q9SAR5}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9SAR5}; Cytoplasmic side {ECO:0000250|UniProtKB:Q9SAR5}. |
| Modified Residue |
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| Post Translational Modification |
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| Signal Peptide |
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| Structure 3D |
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| Cross Reference PDB |
- |
| Mapped Pubmed ID |
12218065;
12499372;
17317660;
18193034;
18775970;
21730198;
24529374;
27247031;
28627464;
|
| Motif |
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| Gene Encoded By |
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| Mass |
36,899 |
| Kinetics |
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| Metal Binding |
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| Rhea ID |
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| Cross Reference Brenda |
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