Detail Information for IndEnz0018000088
IED ID IndEnz0018000088
Enzyme Type ID peroxidase000088
Protein Name Catalase
EC 1.11.1.6
Gene Name
Organism Penicillium janthinellum (Penicillium vitale)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Penicillium Penicillium janthinellum (Penicillium vitale)
Enzyme Sequence TASGKLQRKFLDRFAISMGRGVALGKTYGTLGAASRGATLLQDLLFTEIIFAFDRERVPERAVHARGTGAHGTFLSYEDWSNLTAASFLSAEGKFTPEMTRFSTVSGARGSADTARDVHGFATRFYVDEGNFDIVGNNIPVFFIWDVIIEPTLMALHAQKPNPRFHLPRGQQDPNRISDNLTARGDSLAQGSQISSERGSPKAYSNTEPNKHRSFRLVTDNGKQFQCSNHWQPLQGFIDLGVEEAWRFPEEGEGYVAENLFESIELLTVGDEELEIQSMSFNNDLRERFNSSEVTKSSVVRLVPLITQGKLVFNKNIQMLFNEVIGAMFQPGHIVRGVDFTEDPLLQGRLFSYLDTQLNRHGPNIQQLGFNRPPRAPIHNNNRDGAGEMIDLPPFASFVETQEWGAKDIKQTAVGQNKFDQEHRFSHWKFGVNGFVHTRNDDNVTHARGFFTAPERGQQKKRVAAFDRMFTVVGLSVDGQQANSDQYADFDAAAGKKVAKAIGVEAPKPNSNYFHPTDVFGEHIAASGTKYGVPEGNTKGVLLASVNKPASIAQGAKLQVVASSGDFAEFFISAKQLNMREVTQGIIPLVPVLKLAKLDLGKTFRFQLMQVGNIEELERFGFDLPDLTDKQVDLSAMGMFETTFRPTSRAAQFEQGKTKLVKGLQGKNAFMDRALKQPSNNREKIQRFADRFAVQD
Enzyme Length 696
Uniprot Accession Number P81138
Absorption
Active Site ACT_SITE 64; /evidence=ECO:0000255|PROSITE-ProRule:PRU10013; ACT_SITE 137; /evidence=ECO:0000255|PROSITE-ProRule:PRU10013
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=2 H2O2 = 2 H2O + O2; Xref=Rhea:RHEA:20309, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240; EC=1.11.1.6; Evidence={ECO:0000255|PROSITE-ProRule:PRU10013};
DNA Binding
EC Number 1.11.1.6
Enzyme Function FUNCTION: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Chain (1); Metal binding (1); Region (1)
Keywords Direct protein sequencing;Heme;Hydrogen peroxide;Iron;Metal-binding;Oxidoreductase;Peroxidase
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 77,404
Kinetics
Metal Binding METAL 353; /note=Iron (heme axial ligand); /evidence=ECO:0000250
Rhea ID RHEA:20309
Cross Reference Brenda