Detail Information for IndEnz0018000171
IED ID IndEnz0018000171
Enzyme Type ID peroxidase000171
Protein Name Glutathione S-transferase PM239X14
EC 2.5.1.18
GST class-phi
Gene Name
Organism Arabidopsis thaliana (Mouse-ear cress)
Taxonomic Lineage cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress)
Enzyme Sequence MVTVKLYGMAYSTCTKRVYTTAKEIGVDVKIVPVDLMKGEHKEPAYLDNYHPFGVIPVLEDEDGTKIYESRAISRYLVAKYGKGSSLLPSPSDPKAYGLFEQAASVEYSSFDPPASSLAYERVFAGMRGLKTNEELAKKYVDTLNAKMDGYERILSKQKYLAGNDFTLADLFHLPYGAMVAQLEPTVLDSKPHVKAWWAASLRVIPGRLLRNSSKEFM
Enzyme Length 218
Uniprot Accession Number P42769
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=glutathione + RX = a halide anion + an S-substituted glutathione + H(+); Xref=Rhea:RHEA:16437, ChEBI:CHEBI:15378, ChEBI:CHEBI:16042, ChEBI:CHEBI:17792, ChEBI:CHEBI:57925, ChEBI:CHEBI:90779; EC=2.5.1.18;
DNA Binding
EC Number 2.5.1.18
Enzyme Function FUNCTION: Specifically catalyzes the conjugation of synthetic 1-chloro-2,4-ditrobenzene to GSH. Also functions as a glutathione peroxidase, converting linoleate oxidation products into their corresponding hydroxyacids. This enzyme may thus serve to protect the cell from oxygen toxicity as well as from exogenous toxins such as herbicides. {ECO:0000269|PubMed:8375395}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Domain (2); Region (4)
Keywords Cytoplasm;Detoxification;Oxidoreductase;Peroxidase;Stress response;Transferase
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000305}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 24,364
Kinetics
Metal Binding
Rhea ID RHEA:16437
Cross Reference Brenda