Detail Information for IndEnz0018000205
IED ID IndEnz0018000205
Enzyme Type ID peroxidase000205
Protein Name Catalase
EC 1.11.1.6
Gene Name VVA0294
Organism Vibrio vulnificus (strain YJ016)
Taxonomic Lineage cellular organisms Bacteria Proteobacteria Gammaproteobacteria Vibrionales Vibrionaceae Vibrio Vibrio vulnificus Vibrio vulnificus (strain YJ016)
Enzyme Sequence MHMSKSFLLISMGLASISVHAQTLTRDNGAPVGDNQNSITAGENGSVLLQDVHLIQKLQRFARERIPERVVHARGTGAHGEFVASGDFSDLTLSSPFAQSGKVTPVFVRFSTVIHSKGSPETLRDPRGFATKFYTDQGNWDLVGNNLPVFFIRDSIKFPDMVHSLKPSPVTNLQDPNRFFDFFSSQPSATNMLTWVYTNLGTPASYRTMDGFGVHAYKWINQKGEVNYVKFHWKSQQGVKSLRPAEVTKVQGEDFNHLTNDLYTQINAGNFPKWDLYVKVLSPKALSKLDYNGLDATKVWLDVPEKKVGTMTLNRVPDNFFLETEQSAFAPSNIIPGIEPSEDRLLQGRLFAYADTQLYRLGANLFQLPVNSPKSPVANHNQDGPSNNSTGLGNVDSLDVNYEPSRLVNLTVDKQARAVETPLSGHVQQQAIRNPRDFFQAGVLYRSLSEQDKADLIHNLSGDLNKVNDAEVKAIMVSYFYRADKEYGTRLAKATDVNLKQVTKLASM
Enzyme Length 508
Uniprot Accession Number Q7MFM6
Absorption
Active Site ACT_SITE 72; /evidence=ECO:0000255|PROSITE-ProRule:PRU10013; ACT_SITE 145; /evidence=ECO:0000255|PROSITE-ProRule:PRU10013
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=2 H2O2 = 2 H2O + O2; Xref=Rhea:RHEA:20309, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240; EC=1.11.1.6; Evidence={ECO:0000255|PROSITE-ProRule:PRU10013};
DNA Binding
EC Number 1.11.1.6
Enzyme Function FUNCTION: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Chain (1); Metal binding (1); Region (1); Signal peptide (1)
Keywords Heme;Hydrogen peroxide;Iron;Metal-binding;Oxidoreductase;Periplasm;Peroxidase;Reference proteome;Signal
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Periplasm {ECO:0000305}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..21; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 56,608
Kinetics
Metal Binding METAL 353; /note=Iron (heme axial ligand); /evidence=ECO:0000250
Rhea ID RHEA:20309
Cross Reference Brenda