| IED ID | IndEnz0018000235 |
| Enzyme Type ID | peroxidase000235 |
| Protein Name |
Putative ascorbate peroxidase EC 1.11.1.11 HvAPX1 |
| Gene Name | APX1 |
| Organism | Hydra viridissima (Green hydra) (Chlorohydra viridissima) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Cnidaria Hydrozoa (hydrozoans) Hydroidolina Anthoathecata Aplanulata Hydridae (hydras) Hydra Hydra viridissima (Green hydra) (Chlorohydra viridissima) |
| Enzyme Sequence | MVPVIWLTVLIVLVDSLQIIPTFHDFQRAKTDLLGLIESVKRGDDLPMIAGTVRLAFHDCIGKGKCDGCIDHSKPGNAGLKRVTDRLDALYDASYKGKISRADFYALASVTALTRSTANLSDKYNGLRKFKVGRKDCSTSPVESIDSSDIPRGSDGTSKTLQFFKSEFGMKTQEAVALLGAHTLGRCSLQNSGFVGSWVDQRFSTAPPGEENLSPTSILDNAYYRMIIDIVPWTQVNINGTRIQWQEPSNSIPNDKLPESKRSPLLLNSDMAISWIIKPSDALGTVSCRPTSLKTPCRHSNAHTFAKIYAKNNALWVKDFTKAFNKMIEMNENKLRKAPIFNGYFDEMNSHDEPINESVDEISEDIF |
| Enzyme Length | 367 |
| Uniprot Accession Number | Q539E5 |
| Absorption | |
| Active Site | ACT_SITE 58; /note=Proton acceptor; /evidence=ECO:0000255|PROSITE-ProRule:PRU00297 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=H2O2 + L-ascorbate = 2 H2O + L-dehydroascorbate; Xref=Rhea:RHEA:22996, ChEBI:CHEBI:15377, ChEBI:CHEBI:16240, ChEBI:CHEBI:38290, ChEBI:CHEBI:58539; EC=1.11.1.11; |
| DNA Binding | |
| EC Number | 1.11.1.11 |
| Enzyme Function | FUNCTION: May play a role in the protection of oocyte incorporated cells from rapid apoptotic degradation. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Disulfide bond (1); Glycosylation (3); Signal peptide (1); Site (1) |
| Keywords | Disulfide bond;Glycoprotein;Heme;Hydrogen peroxide;Iron;Metal-binding;Oxidoreductase;Peroxidase;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..16; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 40,790 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | RHEA:22996 |
| Cross Reference Brenda |