Detail Information for IndEnz0018000241
IED ID IndEnz0018000241
Enzyme Type ID peroxidase000241
Protein Name Cytochrome c peroxidase, mitochondrial
CCP
EC 1.11.1.5
Gene Name ccp1 AN10220
Organism Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Aspergillus Aspergillus subgen. Nidulantes Emericella nidulans (Aspergillus nidulans) Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Enzyme Sequence MASAARSASRAFLRSSLRPAVRSSRFALPTQGLRVASRRGYSSEASSGKSSNTLLWAGVALAGGAGAYFYLQGGDVGASTKVFTPTKEDYQKVYNAIAERLANETDYDDGSYGPVLVRLAWHASGTYDAETGTGGSNGATMRFAPESDHGANAGLKYARDFLEPIKAKFPWITYSDLWTLAGACAIQELGGPDIPWRPGRQDKDVSGCTPDGRLPDATKNQDHIRAIFGRMGFDDREMVALIGAHALGRAHTDRSGFDGPWNFSPTVFTNEFFRLLVEEKWQPRKWNGPKQFTDNTTKTLMMFPTDLALVQDKGFRKHVERYAKDSDAFFKEFSEVFVKLLELGVPFNSKVEDRYVFKRSE
Enzyme Length 361
Uniprot Accession Number P0C0V3
Absorption
Active Site ACT_SITE 122; /note="Proton acceptor"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00297, ECO:0000255|PROSITE-ProRule:PRU10012"; ACT_SITE 261; /note="Tryptophan radical intermediate"; /evidence="ECO:0000250"
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=2 Fe(II)-[cytochrome c] + 2 H(+) + H2O2 = 2 Fe(III)-[cytochrome c] + 2 H2O; Xref=Rhea:RHEA:16581, Rhea:RHEA-COMP:10350, Rhea:RHEA-COMP:14399, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16240, ChEBI:CHEBI:29033, ChEBI:CHEBI:29034; EC=1.11.1.5;
DNA Binding
EC Number 1.11.1.5
Enzyme Function FUNCTION: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Chain (1); Erroneous gene model prediction (1); Metal binding (1); Site (1); Transit peptide (1)
Keywords Heme;Iron;Metal-binding;Mitochondrion;Oxidoreductase;Peroxidase;Reference proteome;Transit peptide
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 39,937
Kinetics
Metal Binding METAL 245; /note=Iron (heme b axial ligand)
Rhea ID RHEA:16581
Cross Reference Brenda