IED ID | IndEnz0018000241 |
Enzyme Type ID | peroxidase000241 |
Protein Name |
Cytochrome c peroxidase, mitochondrial CCP EC 1.11.1.5 |
Gene Name | ccp1 AN10220 |
Organism | Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) |
Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Aspergillus Aspergillus subgen. Nidulantes Emericella nidulans (Aspergillus nidulans) Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) |
Enzyme Sequence | MASAARSASRAFLRSSLRPAVRSSRFALPTQGLRVASRRGYSSEASSGKSSNTLLWAGVALAGGAGAYFYLQGGDVGASTKVFTPTKEDYQKVYNAIAERLANETDYDDGSYGPVLVRLAWHASGTYDAETGTGGSNGATMRFAPESDHGANAGLKYARDFLEPIKAKFPWITYSDLWTLAGACAIQELGGPDIPWRPGRQDKDVSGCTPDGRLPDATKNQDHIRAIFGRMGFDDREMVALIGAHALGRAHTDRSGFDGPWNFSPTVFTNEFFRLLVEEKWQPRKWNGPKQFTDNTTKTLMMFPTDLALVQDKGFRKHVERYAKDSDAFFKEFSEVFVKLLELGVPFNSKVEDRYVFKRSE |
Enzyme Length | 361 |
Uniprot Accession Number | P0C0V3 |
Absorption | |
Active Site | ACT_SITE 122; /note="Proton acceptor"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00297, ECO:0000255|PROSITE-ProRule:PRU10012"; ACT_SITE 261; /note="Tryptophan radical intermediate"; /evidence="ECO:0000250" |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | CATALYTIC ACTIVITY: Reaction=2 Fe(II)-[cytochrome c] + 2 H(+) + H2O2 = 2 Fe(III)-[cytochrome c] + 2 H2O; Xref=Rhea:RHEA:16581, Rhea:RHEA-COMP:10350, Rhea:RHEA-COMP:14399, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16240, ChEBI:CHEBI:29033, ChEBI:CHEBI:29034; EC=1.11.1.5; |
DNA Binding | |
EC Number | 1.11.1.5 |
Enzyme Function | FUNCTION: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. {ECO:0000250}. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Active site (2); Chain (1); Erroneous gene model prediction (1); Metal binding (1); Site (1); Transit peptide (1) |
Keywords | Heme;Iron;Metal-binding;Mitochondrion;Oxidoreductase;Peroxidase;Reference proteome;Transit peptide |
Interact With | |
Induction | |
Subcellular Location | SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250}. |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | - |
Motif | |
Gene Encoded By | |
Mass | 39,937 |
Kinetics | |
Metal Binding | METAL 245; /note=Iron (heme b axial ligand) |
Rhea ID | RHEA:16581 |
Cross Reference Brenda |