| IED ID | IndEnz0018000272 |
| Enzyme Type ID | peroxidase000272 |
| Protein Name |
Catalase isozyme C EC 1.11.1.6 |
| Gene Name | OsI_09857 |
| Organism | Oryza sativa subsp. indica (Rice) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae Liliopsida Petrosaviidae commelinids Poales Poaceae BOP clade Oryzoideae Oryzeae Oryzinae Oryza Oryza sativa (Rice) Oryza sativa subsp. indica (Rice) |
| Enzyme Sequence | MDPYKHRPSSSFNGPLWSTNSGAPVWNNNNSLTVGSRGPILLEDYHLVEKLANFDRERIPERVVHARGASAKGFFEVTHDITHLTCADFLRAPGVQTPVIVRFSTVIHERGSPETLRDPRGFAIKFYTREGNWDLVGNNFPVFFIRDGMKFPDMVHSLKPNPKSHVQENWRILDFFSHHPESLHMFTFLFDDIGIPADYRHMDGSGVNTYTLVNRAGKSHYVKFHWKPTCGVKSLLDDEAVTVGGTNHSHATQDLYDSIAAGNFPEWKLFIQTIDPDHEDRFDFDPLDVTKTWPEDIVPLQPVGRMVLNRNIDNFFSENEQLAFCPGIIVPGIYYSDDKLLQTRIFSYSDTQRHRLGPNYLLLPPNAPKCAHHNNHYDGFMNFMHRDEEVDYFPSRYDPAKHAPRYPIPSATLTGRREKVVIAKENNFKQPGERYRSWDPARQDRFIKRWIDALSDPRLTHEIRSIWLSYWSQADRSLGQKLASRLSAKPSM |
| Enzyme Length | 492 |
| Uniprot Accession Number | B8AME2 |
| Absorption | |
| Active Site | ACT_SITE 65; /evidence=ECO:0000255|PROSITE-ProRule:PRU10013; ACT_SITE 138; /evidence=ECO:0000250|UniProtKB:Q9C168 |
| Activity Regulation | |
| Binding Site | BINDING 62; /note=Heme; /evidence=ECO:0000250|UniProtKB:Q9C168; BINDING 102; /note=Heme; /evidence=ECO:0000250|UniProtKB:Q9C168; BINDING 151; /note=Heme; /evidence=ECO:0000250|UniProtKB:Q9C168; BINDING 344; /note=Heme; /evidence=ECO:0000250|UniProtKB:Q9C168; BINDING 355; /note=Heme; /evidence=ECO:0000250|UniProtKB:Q9C168 |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=2 H2O2 = 2 H2O + O2; Xref=Rhea:RHEA:20309, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240; EC=1.11.1.6; Evidence={ECO:0000255|PROSITE-ProRule:PRU10013}; |
| DNA Binding | |
| EC Number | 1.11.1.6 |
| Enzyme Function | FUNCTION: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Responsible for the redox homeostasis in leaves. Prevents nitric oxide (NO) accumulation and subsequent NO-mediated leaf cell death as well as the S-nitrosylation of specific proteins (e.g. glyceraldehyde 3-phosphate dehydrogenase and thioredoxin) by degrading H(2)O(2). Involved in photorespiration. Promotes drought stress tolerance and recovery. Involved in NO-mediated enhanced tolerance to zinc oxide nanoparticles (ZnO NPs)-induced phytotoxicity. Participates in melatonin-mediated detoxification. {ECO:0000250|UniProtKB:Q10S82}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Binding site (5); Chain (1); Cross-link (1); Metal binding (1); Modified residue (1); Motif (1) |
| Keywords | Cell membrane;Glyoxysome;Heme;Hydrogen peroxide;Iron;Membrane;Metal-binding;Oxidoreductase;Peroxidase;Peroxisome;Phosphoprotein;Reference proteome;Stress response;Thioether bond |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Peroxisome {ECO:0000250|UniProtKB:Q10S82}. Glyoxysome {ECO:0000250|UniProtKB:Q10S82}. Cell membrane {ECO:0000250|UniProtKB:Q10S82}. |
| Modified Residue | MOD_RES 210; /note=Phosphotyrosine; by STRK1; /evidence=ECO:0000250|UniProtKB:Q10S82 |
| Post Translational Modification | PTM: Activated by STRK1-mediated phosphorylation at Tyr-210 upon salt and oxidative stress. {ECO:0000250|UniProtKB:Q10S82}. |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | MOTIF 484..492; /note=Peroxisome targeting signal; /evidence=ECO:0000305 |
| Gene Encoded By | |
| Mass | 56,764 |
| Kinetics | |
| Metal Binding | METAL 348; /note=Iron (heme axial ligand); /evidence=ECO:0000250|UniProtKB:Q9C168 |
| Rhea ID | RHEA:20309 |
| Cross Reference Brenda |