| IED ID | IndEnz0018000321 |
| Enzyme Type ID | peroxidase000321 |
| Protein Name |
Respiratory burst oxidase homolog protein C EC 1.11.1.- EC 1.6.3.- NADPH oxidase RBOHC AtRBOHC Protein ROOT HAIR DEFECTIVE 2 |
| Gene Name | RBOHC RHD2 At5g51060 K3K7.25 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress) |
| Enzyme Sequence | MSRVSFEVSGGYHSDAEAGNSGPMSGGQLPPIYKKPGNSRFTAENSQRTRTAPYVDLTVDVQDDTVSVHSLKMEGGSSVEESPELTLLKRNRLEKKTTVVKRLASVSHELKRLTSVSGGIGGRKPPRPAKLDRTKSAASQALKGLKFISKTDGGAGWSAVEKRFNQITATTGGLLLRTKFGECIGMTSKDFALELFDALARRRNITGEVIDGDQLKEFWEQINDQSFDSRLKTFFDMVDKDADGRLTEDEVREIISLSASANNLSTIQKRADEYAALIMEELDPDNIGYIMLESLETLLLQAATQSVITSTGERKNLSHMMSQRLKPTFNRNPLKRWYRGLRFFLLDNWQRCWVIVLWFIVMAILFTYKYIQYRRSPVYPVMGDCVCMAKGAAETVKLNMALILLPVCRNTITWLRNKTRLGRVVPFDDNLNFHKVIAVGIIVGVTMHAGAHLACDFPRLLHATPEAYRPLRQFFGDEQPKSYWHFVNSVEGITGLVMVLLMAIAFTLATPWFRRGKLNYLPGPLKKLASFNAFWYTHHLFVIVYILLVAHGYYLYLTRDWHNKTTWMYLVVPVVLYACERLIRAFRSSIKAVTIRKVAVYPGNVLAIHLSRPQNFKYKSGQYMFVNCAAVSPFEWHPFSITSAPQDDYLSVHIRVLGDWTRALKGVFSEVCKPPPAGVSGLLRADMLHGANNPDFPKVLIDGPYGAPAQDYKKYEVVLLVGLGIGATPMISIVKDIVNNIKAKEQAQLNRMENGTSEPQRSKKESFRTRRAYFYWVTREQGSFDWFKNIMNEVAERDANRVIEMHNYCTSVYEEGDARSALIHMLQSLNHAKNGVDIVSGTRVMSHFAKPNWRNVYKRIAMDHPNTKVGVFYCGAPALTKELRHLALDFTHKTSTRFSFHKENF |
| Enzyme Length | 905 |
| Uniprot Accession Number | O81210 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 1.11.1.-; 1.6.3.- |
| Enzyme Function | FUNCTION: Calcium-dependent NADPH oxidase that generates superoxide. Required for H(2)O(2) production in response to K(+) deficiency and for the generation of reactive oxygen species (ROS) that regulate cell expansion through the activation of Ca(2+) channels. {ECO:0000269|PubMed:12660786, ECO:0000269|PubMed:15173595}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Domain (4); Erroneous gene model prediction (1); Metal binding (5); Modified residue (3); Region (3); Sequence conflict (2); Topological domain (7); Transmembrane (6) |
| Keywords | Calcium;FAD;Flavoprotein;Membrane;Metal-binding;NADP;Oxidoreductase;Peroxidase;Phosphoprotein;Reference proteome;Repeat;Transmembrane;Transmembrane helix |
| Interact With | |
| Induction | INDUCTION: By potassium starvation. {ECO:0000269|PubMed:15173595}. |
| Subcellular Location | SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
| Modified Residue | MOD_RES 25; /note=Phosphoserine; /evidence=ECO:0000250|UniProtKB:Q9FIJ0; MOD_RES 318; /note=Phosphoserine; /evidence=ECO:0000250|UniProtKB:Q9FIJ0; MOD_RES 322; /note=Phosphoserine; /evidence=ECO:0000250|UniProtKB:Q9FIJ0 |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 10898772; 10898773; 12354956; 15908600; 15923322; 16212611; 16355224; 17301029; 18309082; 18317797; 18408046; 18643991; 19220789; 20637647; 21976360; 22001402; 22383108; 22730426; 22751303; 23266413; 23700086; 24833217; 26765289; 28751315; 29490083; 29992537; 30097007; 30154812; 30380363; 30570803; 32172758; 32179566; 33042167; 9390433; |
| Motif | |
| Gene Encoded By | |
| Mass | 102,518 |
| Kinetics | |
| Metal Binding | METAL 239; /note=Calcium; /evidence=ECO:0000255|PROSITE-ProRule:PRU00448; METAL 241; /note=Calcium; /evidence=ECO:0000255|PROSITE-ProRule:PRU00448; METAL 243; /note=Calcium; /evidence=ECO:0000255|PROSITE-ProRule:PRU00448; METAL 245; /note=Calcium; via carbonyl oxygen; /evidence=ECO:0000255|PROSITE-ProRule:PRU00448; METAL 250; /note=Calcium; /evidence=ECO:0000255|PROSITE-ProRule:PRU00448 |
| Rhea ID | |
| Cross Reference Brenda |