Detail Information for IndEnz0018000342
IED ID IndEnz0018000342
Enzyme Type ID peroxidase000342
Protein Name Glutathione S-transferase 1
EC 2.5.1.18
GST-I
Gene Name GTT1 YIR038C
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Saccharomycotina (true yeasts) Saccharomycetes Saccharomycetales Saccharomycetaceae Saccharomyces Saccharomyces cerevisiae (Baker's yeast) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Enzyme Sequence MSLPIIKVHWLDHSRAFRLLWLLDHLNLEYEIVPYKRDANFRAPPELKKIHPLGRSPLLEVQDRETGKKKILAESGFIFQYVLQHFDHSHVLMSEDADIADQINYYLFYVEGSLQPPLMIEFILSKVKDSGMPFPISYLARKVADKISQAYSSGEVKNQFDFVEGEISKNNGYLVDGKLSGADILMSFPLQMAFERKFAAPEDYPAISKWLKTITSEESYAASKEKARALGSNF
Enzyme Length 234
Uniprot Accession Number P40582
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=glutathione + RX = a halide anion + an S-substituted glutathione + H(+); Xref=Rhea:RHEA:16437, ChEBI:CHEBI:15378, ChEBI:CHEBI:16042, ChEBI:CHEBI:17792, ChEBI:CHEBI:57925, ChEBI:CHEBI:90779; EC=2.5.1.18;
DNA Binding
EC Number 2.5.1.18
Enzyme Function
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Domain (2)
Keywords Endoplasmic reticulum;Membrane;Reference proteome;Transferase
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Peripheral membrane protein.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 11283351; 12684511; 14690591; 15032872; 15456898; 15475181; 15766533; 16709151; 16915356; 16936141; 17156009; 17157989; 17651441; 18199684; 18467557; 18719252; 19017464; 19098979; 19854949; 21549177; 21734149; 21820081; 21918511; 22094416; 22209905; 22615054; 23275493; 23409974; 24376879; 24516431; 24868093; 25240850; 27708136;
Motif
Gene Encoded By
Mass 26,795
Kinetics
Metal Binding
Rhea ID RHEA:16437
Cross Reference Brenda