Detail Information for IndEnz0018000407
IED ID IndEnz0018000407
Enzyme Type ID peroxidase000407
Protein Name Low-redox potential peroxidase
EC 1.11.1.7
Putative ligninolytic peroxidase
Gene Name LnP
Organism Taiwanofungus camphoratus (Poroid brown-rot fungus) (Antrodia camphorata)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Basidiomycota Agaricomycotina Agaricomycetes Agaricomycetes incertae sedis Polyporales Polyporales incertae sedis Taiwanofungus Taiwanofungus camphoratus (Poroid brown-rot fungus) (Antrodia camphorata)
Enzyme Sequence MRSSTHIFVSFVVYCGVFVTSAIALSNHTNAYQCDRWSNVLNELQANLFHEGQCRSAALRASGTFGGGGADGSIIQFAHTELAYPANEGLEEMVYTLKHFADGHEVSYGDMIQFAGAVALSNCPGSPRLRFYAGRPEAIAPSPPNLLPLPTDPVEKILSRMADAGFNAGDTVALLAAHSIAVQNTIDPSIPDSPLDSTPRIFDTQFYLETLLRGTRYPGKGRGPAQSKSPIEHEFRLASDAAIARHTSTACEWQSFIDNQEGLRSAFRNAMVKLANQGHDNLVDCSFVIPVPPPWNLPVEYPSGKSRSDVEQSCSDVPFPTISLNSDVHD
Enzyme Length 330
Uniprot Accession Number C0IW58
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O; Xref=Rhea:RHEA:56136, ChEBI:CHEBI:15377, ChEBI:CHEBI:16240, ChEBI:CHEBI:139520, ChEBI:CHEBI:139521; EC=1.11.1.7;
DNA Binding
EC Number 1.11.1.7
Enzyme Function FUNCTION: Can oxidize the lignin redox mediator veratryl alcohol to veratryl aldehyde. May be involved in oxidation of lignocellulose substrates. {ECO:0000269|PubMed:19202090}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Disulfide bond (3); Glycosylation (1); Metal binding (8); Sequence conflict (3); Signal peptide (1)
Keywords Calcium;Disulfide bond;Glycoprotein;Heme;Hydrogen peroxide;Iron;Metal-binding;Oxidoreductase;Peroxidase;Secreted;Signal
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted {ECO:0000255|PROSITE-ProRule:PRU00297, ECO:0000269|PubMed:19202090}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..24; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 35,770
Kinetics BIOPHYSICOCHEMICAL PROPERTIES: Kinetic parameters: KM=13.1 uM for veratryl alcohol {ECO:0000269|PubMed:19202090};
Metal Binding METAL 69; /note=Calcium 1; via carbonyl oxygen; /evidence=ECO:0000255|PROSITE-ProRule:PRU00297; METAL 71; /note=Calcium 1; /evidence=ECO:0000255|PROSITE-ProRule:PRU00297; METAL 73; /note=Calcium 1; /evidence=ECO:0000255|PROSITE-ProRule:PRU00297; METAL 178; /note=Iron (heme b axial ligand); /evidence=ECO:0000255|PROSITE-ProRule:PRU00297; METAL 179; /note=Calcium 2; /evidence=ECO:0000255|PROSITE-ProRule:PRU00297; METAL 196; /note=Calcium 2; /evidence=ECO:0000255|PROSITE-ProRule:PRU00297; METAL 198; /note=Calcium 2; /evidence=ECO:0000255|PROSITE-ProRule:PRU00297; METAL 203; /note=Calcium 2; /evidence=ECO:0000255|PROSITE-ProRule:PRU00297
Rhea ID RHEA:56136
Cross Reference Brenda