Detail Information for IndEnz0018000409
IED ID IndEnz0018000409
Enzyme Type ID peroxidase000409
Protein Name Glutathione S-transferase
EC 2.5.1.18
Fragment
Gene Name
Organism Lactiplantibacillus plantarum (Lactobacillus plantarum)
Taxonomic Lineage cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Lactobacillales Lactobacillaceae Lactiplantibacillus Lactiplantibacillus plantarum (Lactobacillus plantarum)
Enzyme Sequence YLFVMTNRMKLLNYSFEGLPNLKKLDEIMRQHPAVKRVLEQEGAPHTLTD
Enzyme Length 50
Uniprot Accession Number C0HLL7
Absorption
Active Site
Activity Regulation ACTIVITY REGULATION: Inhibited by Fe(2+) and DTT. Slightly inhibited by SDS and Zn(2+). Activity is slightly increased by Mn(2+). {ECO:0000269|PubMed:32181246}.
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=glutathione + RX = a halide anion + an S-substituted glutathione + H(+); Xref=Rhea:RHEA:16437, ChEBI:CHEBI:15378, ChEBI:CHEBI:16042, ChEBI:CHEBI:17792, ChEBI:CHEBI:57925, ChEBI:CHEBI:90779; EC=2.5.1.18; Evidence={ECO:0000269|PubMed:32181246};
DNA Binding
EC Number 2.5.1.18
Enzyme Function FUNCTION: Glutathione S-transferase, which conjugates reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. {ECO:0000269|PubMed:32181246}.
Temperature Dependency BIOPHYSICOCHEMICAL PROPERTIES: Temperature dependence: Optimum temperature is 40 degrees Celsius. {ECO:0000269|PubMed:32181246};
PH Dependency BIOPHYSICOCHEMICAL PROPERTIES: pH dependence: Optimum pH is 6. {ECO:0000269|PubMed:32181246};
Pathway
nucleotide Binding
Features Chain (1); Non-terminal residue (1)
Keywords Direct protein sequencing;Transferase
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 5,887
Kinetics
Metal Binding
Rhea ID RHEA:16437
Cross Reference Brenda