Detail Information for IndEnz0018000418
IED ID IndEnz0018000418
Enzyme Type ID peroxidase000418
Protein Name Catalase-peroxidase
CP
EC 1.11.1.21
Peroxidase/catalase
Gene Name katG Hsero_1242
Organism Herbaspirillum seropedicae (strain SmR1)
Taxonomic Lineage cellular organisms Bacteria Proteobacteria Betaproteobacteria Burkholderiales Oxalobacteraceae Herbaspirillum Herbaspirillum seropedicae Herbaspirillum seropedicae (strain SmR1)
Enzyme Sequence MSNEAKCPFNHTAGSGTSNRDWWPKQLRVDLLAQHSSKSNPMGEDFDYAEAFKSLDLAAVKADLAKVMTDSQDWWPADFGHYGPLFVRMAWHSAGTYRIGDGRGGAGRGQQRFAPLNSWPDNVNLDKARRLLWPVKQKYGNKISWADLLILTGNVALETMGFKTFGFAGGRADVWEPDLDVYWGTESTWLGGDDRYGKGKGSSSQGEIPADAHRHGQEQARTAPAGRNLENPLAAVQMGLIYVNPEGPEGNPDPLAAAHDIRETFARMAMDDEETVALIAGGHTFGKTHGAGDAKHVGREPEGEDMDSQGLGWKSSFGSGVGGDTISSGLEVTWTQTPAQWSNYFFENLFKYEWELTKSPAGAHQWVAKGADAVIPHAHGGAPLLPTMLTTDLSLRFDPAYEKISRRFLEHPEQFADAFARAWFKLTHRDLGPRSRYLGPEVPAEELIWQDPLPQAEGAQIDAADVAALKAKVLGSGLSVPELVATAWASASTFRGGDMRGGANGARIRLAPQKDWAANQPAQLAKVLKTLEGIQSAFNQGGKKVSLADLIVLAGSAAVEKAAQDAGVAVAVPFRAGRVDASQEQTDAASFAPLEPIVDGFRNFQKQRYAVRGEDMLIDKAQQLTLSAPEMTVLVGGLRVLGNNVGGSTKGMFTDRVGVLSNDFFVNLLDMATEWKSTSPAQEEFEGRDRKTGAVKWAGTRVDLVFGSNAVLRALAEVYASADAKEKFVKDFVAAWVKVMELDRFDLK
Enzyme Length 748
Uniprot Accession Number D8INT8
Absorption
Active Site ACT_SITE 92; /note=Proton acceptor; /evidence=ECO:0000250
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=AH2 + H2O2 = A + 2 H2O; Xref=Rhea:RHEA:30275, ChEBI:CHEBI:13193, ChEBI:CHEBI:15377, ChEBI:CHEBI:16240, ChEBI:CHEBI:17499; EC=1.11.1.21; CATALYTIC ACTIVITY: Reaction=2 H2O2 = 2 H2O + O2; Xref=Rhea:RHEA:20309, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240; EC=1.11.1.21;
DNA Binding
EC Number 1.11.1.21
Enzyme Function FUNCTION: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1); Compositional bias (1); Cross-link (2); Metal binding (1); Region (2); Site (1)
Keywords Heme;Hydrogen peroxide;Iron;Metal-binding;Oxidoreductase;Peroxidase;Reference proteome
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification PTM: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme. {ECO:0000250}.
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 81,181
Kinetics
Metal Binding METAL 283; /note=Iron (heme b axial ligand); /evidence=ECO:0000250
Rhea ID RHEA:30275; RHEA:20309
Cross Reference Brenda